Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I

We report the synthesis of 2,3-dihydro-1,3,4-thiadiazoles and 1,3,4-thiadiazoles from 1,2:3,4-di-O-isopropylidene-α-D-galacto-1,6-hexodialdo-1,5-pyranose thiosemicarbazone. The physical and spectroscopic characterizations of the heterocyclic derivatives as well as the intermediate product are descri...

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Autores principales: Martins Alho, Miriam Amelia, D'Accorso, Norma Beatriz
Publicado: 1997
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v34_n5_p1415_MartinsAlho
http://hdl.handle.net/20.500.12110/paper_0022152X_v34_n5_p1415_MartinsAlho
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_0022152X_v34_n5_p1415_MartinsAlho
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spelling paper:paper_0022152X_v34_n5_p1415_MartinsAlho2023-06-08T14:46:45Z Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I Martins Alho, Miriam Amelia D'Accorso, Norma Beatriz We report the synthesis of 2,3-dihydro-1,3,4-thiadiazoles and 1,3,4-thiadiazoles from 1,2:3,4-di-O-isopropylidene-α-D-galacto-1,6-hexodialdo-1,5-pyranose thiosemicarbazone. The physical and spectroscopic characterizations of the heterocyclic derivatives as well as the intermediate product are described. We present the prefered conformation in solution using computational calculations and spectroscopic data. The possibilities of chiral induction of the cyclization reaction are discussed. Fil:Martins Alho, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:D'Accorso, N.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v34_n5_p1415_MartinsAlho http://hdl.handle.net/20.500.12110/paper_0022152X_v34_n5_p1415_MartinsAlho
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description We report the synthesis of 2,3-dihydro-1,3,4-thiadiazoles and 1,3,4-thiadiazoles from 1,2:3,4-di-O-isopropylidene-α-D-galacto-1,6-hexodialdo-1,5-pyranose thiosemicarbazone. The physical and spectroscopic characterizations of the heterocyclic derivatives as well as the intermediate product are described. We present the prefered conformation in solution using computational calculations and spectroscopic data. The possibilities of chiral induction of the cyclization reaction are discussed.
author Martins Alho, Miriam Amelia
D'Accorso, Norma Beatriz
spellingShingle Martins Alho, Miriam Amelia
D'Accorso, Norma Beatriz
Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
author_facet Martins Alho, Miriam Amelia
D'Accorso, Norma Beatriz
author_sort Martins Alho, Miriam Amelia
title Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
title_short Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
title_full Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
title_fullStr Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
title_full_unstemmed Synthesis and Characterization of some Heterocyclic Derivatives by Cyclization of Carbohydrate Thiosemicarbazones. Part I
title_sort synthesis and characterization of some heterocyclic derivatives by cyclization of carbohydrate thiosemicarbazones. part i
publishDate 1997
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v34_n5_p1415_MartinsAlho
http://hdl.handle.net/20.500.12110/paper_0022152X_v34_n5_p1415_MartinsAlho
work_keys_str_mv AT martinsalhomiriamamelia synthesisandcharacterizationofsomeheterocyclicderivativesbycyclizationofcarbohydratethiosemicarbazonesparti
AT daccorsonormabeatriz synthesisandcharacterizationofsomeheterocyclicderivativesbycyclizationofcarbohydratethiosemicarbazonesparti
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