Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers
Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated ind...
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2010
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00187143_v82_n4_p433_Sala http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala |
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paper:paper_00187143_v82_n4_p433_Sala2023-06-08T14:39:36Z Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers Corach, Daniel Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated individuals were analyzed. The study involved typing fifteen autosomal STRs, nine Y-chromosome STRs, and four biallele loci in the nonrecombinant region of the Y chromosome, sequencing the mtDNA of hypervariable regions I and II, and detecting the 9-bp ins/del in region V of mtDNA. All autosomal STRs were in Hardy-Weinberg equilibrium. The four major native American mtDNA haplogroups were represented in the sample. Haplogroups A2 and D1 exhibited the highest frequencies (40.5% and 36.0%, respectively), and haplogroups B2 and C1 appeared to be less frequent (17.5% and 6.0%, respectively). The native American haplogroup Q1a3a was observed in a relevant proportion (88.8%). In addition, a nine-STR Y-chromosome haplotype (DYS19*13, DYS389I*14, DYS389II*31, DYS390*24, DYS391*11, DYS392*14, DYS393*11, DYS385A*14, DYS385B*16) exhibited a frequency of more than 36%. Our results indicate that the analyzed Argentinean Guaraní individuals are genetically more closely related to Guaraní from Brazil [genetic distance (.μ)2 = 0.48] than to other related tribes that are geographically closer. Statistical approaches based on autosomal data do not support the hypothesis of genetic drift previously proposed; however, this apparent discrepancy might be due to the lack of sensitivity of the autosomal markers used here. © 2010 Wayne State University Press. Fil:Corach, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00187143_v82_n4_p433_Sala http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats |
| spellingShingle |
Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats Corach, Daniel Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| topic_facet |
Autosomal STRs Mbyá-Guaraní mtDNA Native South Amerindian Y-chromosome STRs microsatellite DNA mitochondrial DNA American Indian Argentina article cell nucleus female genetics human male population genetics Y chromosome Argentina Cell Nucleus Chromosomes, Human, Y DNA, Mitochondrial Female Genetics, Population Humans Indians, North American Male Microsatellite Repeats |
| description |
Autosomal STRs, Y-chromosome markers, and mitochondrial DNA sequences were investigated in six Mbyá-Guaraní villages (Fortín M'Bororé, Yryapu, Tabay, Kaaguy Poty, Jejy, and Yaboti), all of them settled within the province of Misiones, northeastern Argentina. One hundred twenty-one unrelated individuals were analyzed. The study involved typing fifteen autosomal STRs, nine Y-chromosome STRs, and four biallele loci in the nonrecombinant region of the Y chromosome, sequencing the mtDNA of hypervariable regions I and II, and detecting the 9-bp ins/del in region V of mtDNA. All autosomal STRs were in Hardy-Weinberg equilibrium. The four major native American mtDNA haplogroups were represented in the sample. Haplogroups A2 and D1 exhibited the highest frequencies (40.5% and 36.0%, respectively), and haplogroups B2 and C1 appeared to be less frequent (17.5% and 6.0%, respectively). The native American haplogroup Q1a3a was observed in a relevant proportion (88.8%). In addition, a nine-STR Y-chromosome haplotype (DYS19*13, DYS389I*14, DYS389II*31, DYS390*24, DYS391*11, DYS392*14, DYS393*11, DYS385A*14, DYS385B*16) exhibited a frequency of more than 36%. Our results indicate that the analyzed Argentinean Guaraní individuals are genetically more closely related to Guaraní from Brazil [genetic distance (.μ)2 = 0.48] than to other related tribes that are geographically closer. Statistical approaches based on autosomal data do not support the hypothesis of genetic drift previously proposed; however, this apparent discrepancy might be due to the lack of sensitivity of the autosomal markers used here. © 2010 Wayne State University Press. |
| author |
Corach, Daniel |
| author_facet |
Corach, Daniel |
| author_sort |
Corach, Daniel |
| title |
Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| title_short |
Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| title_full |
Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| title_fullStr |
Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| title_full_unstemmed |
Genetic analysis of six communities of Mbyá-Guaraní inhabiting Northeastern Argentina by means of nuclear and mitochondrial polymorphic markers |
| title_sort |
genetic analysis of six communities of mbyá-guaraní inhabiting northeastern argentina by means of nuclear and mitochondrial polymorphic markers |
| publishDate |
2010 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00187143_v82_n4_p433_Sala http://hdl.handle.net/20.500.12110/paper_00187143_v82_n4_p433_Sala |
| work_keys_str_mv |
AT corachdaniel geneticanalysisofsixcommunitiesofmbyaguaraniinhabitingnortheasternargentinabymeansofnuclearandmitochondrialpolymorphicmarkers |
| _version_ |
1768545630381146112 |