Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat

The administration of 15(R)-15-methyl prostaglandin E2 (15(R)-15-M-PGE2) in vivo significantly diminished the uptake of59Fe into blood, spleen, liver, femur and dried intestine of rats, whereas acetylsalicylic acid (ASA) increased the counts significantly. This effect of ASA was counteracted by 15(R...

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Detalles Bibliográficos
Publicado:	1982
Materias:	15 methylprostaglandin e2 methyl ester acetylsalicylic acid iron iron 59 radioisotope animal experiment digestive system drug absorption drug interaction drug potentiation intestine absorption oral drug administration pharmacokinetics rat Animal Arbaprostil Aspirin Femur Intestinal Absorption Iron Iron Radioisotopes Liver Male Prostaglandins E, Synthetic Rats Rats, Inbred Strains Spleen Support, Non-U.S. Gov't
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v38_n1_p116_Gutnisky http://hdl.handle.net/20.500.12110/paper_00144754_v38_n1_p116_Gutnisky
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00144754_v38_n1_p116_Gutnisky
record_format	dspace
spelling	paper:paper_00144754_v38_n1_p116_Gutnisky2023-06-08T14:37:08Z Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat 15 methylprostaglandin e2 methyl ester acetylsalicylic acid iron iron 59 radioisotope animal experiment digestive system drug absorption drug interaction drug potentiation intestine absorption oral drug administration pharmacokinetics rat Animal Arbaprostil Aspirin Femur Intestinal Absorption Iron Iron Radioisotopes Liver Male Prostaglandins E, Synthetic Rats Rats, Inbred Strains Spleen Support, Non-U.S. Gov't The administration of 15(R)-15-methyl prostaglandin E2 (15(R)-15-M-PGE2) in vivo significantly diminished the uptake of59Fe into blood, spleen, liver, femur and dried intestine of rats, whereas acetylsalicylic acid (ASA) increased the counts significantly. This effect of ASA was counteracted by 15(R)-15-M-PGE2. It is suggested that prostaglandins (PGs) might play an important role in inhibiting iron absorption at the intestinal level. © 1982 Birkhäuser Verlag. 1982 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v38_n1_p116_Gutnisky http://hdl.handle.net/20.500.12110/paper_00144754_v38_n1_p116_Gutnisky
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	15 methylprostaglandin e2 methyl ester acetylsalicylic acid iron iron 59 radioisotope animal experiment digestive system drug absorption drug interaction drug potentiation intestine absorption oral drug administration pharmacokinetics rat Animal Arbaprostil Aspirin Femur Intestinal Absorption Iron Iron Radioisotopes Liver Male Prostaglandins E, Synthetic Rats Rats, Inbred Strains Spleen Support, Non-U.S. Gov't
spellingShingle	15 methylprostaglandin e2 methyl ester acetylsalicylic acid iron iron 59 radioisotope animal experiment digestive system drug absorption drug interaction drug potentiation intestine absorption oral drug administration pharmacokinetics rat Animal Arbaprostil Aspirin Femur Intestinal Absorption Iron Iron Radioisotopes Liver Male Prostaglandins E, Synthetic Rats Rats, Inbred Strains Spleen Support, Non-U.S. Gov't Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
topic_facet	15 methylprostaglandin e2 methyl ester acetylsalicylic acid iron iron 59 radioisotope animal experiment digestive system drug absorption drug interaction drug potentiation intestine absorption oral drug administration pharmacokinetics rat Animal Arbaprostil Aspirin Femur Intestinal Absorption Iron Iron Radioisotopes Liver Male Prostaglandins E, Synthetic Rats Rats, Inbred Strains Spleen Support, Non-U.S. Gov't
description	The administration of 15(R)-15-methyl prostaglandin E2 (15(R)-15-M-PGE2) in vivo significantly diminished the uptake of59Fe into blood, spleen, liver, femur and dried intestine of rats, whereas acetylsalicylic acid (ASA) increased the counts significantly. This effect of ASA was counteracted by 15(R)-15-M-PGE2. It is suggested that prostaglandins (PGs) might play an important role in inhibiting iron absorption at the intestinal level. © 1982 Birkhäuser Verlag.
title	Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
title_short	Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
title_full	Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
title_fullStr	Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
title_full_unstemmed	Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
title_sort	effect of 15(r)-15-methyl-prostaglandin e2 on iron absorption in the rat
publishDate	1982
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v38_n1_p116_Gutnisky http://hdl.handle.net/20.500.12110/paper_00144754_v38_n1_p116_Gutnisky
_version_	1768541546667311104

Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat

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