Effect of naloxone on the nocturnal rise of rat pineal melatonin content

Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-...

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Publicado: 1984
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rat
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v98_n2_p261_Lowenstein
http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein
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spelling paper:paper_00142999_v98_n2_p261_Lowenstein2023-06-08T14:36:56Z Effect of naloxone on the nocturnal rise of rat pineal melatonin content Endogenous opioids Melatonin Naloxone Norepinephrine Pineal gland endorphin melatonin naloxone neurotransmitter noradrenalin radioisotope animal experiment central nervous system endocrine system nervous system nonhuman noradrenalin h 3 photoperiodicity pineal body rat subcutaneous drug administration synapse Animal Male Melatonin Naloxone Pineal Gland Rats Rats, Inbred Strains Support, Non-U.S. Gov't Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-4M) did not affect either in vitro rat pineal melatonin content or 3H-labeled transmitter release in glands previously incubated with [3H]norepinephrine. Hence a central, rather than a peripheral opioid synapse appears to be involved in naloxone effect on nocturnal melatonin increase. © 1984. 1984 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v98_n2_p261_Lowenstein http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Endogenous opioids
Melatonin
Naloxone
Norepinephrine
Pineal gland
endorphin
melatonin
naloxone
neurotransmitter
noradrenalin
radioisotope
animal experiment
central nervous system
endocrine system
nervous system
nonhuman
noradrenalin h 3
photoperiodicity
pineal body
rat
subcutaneous drug administration
synapse
Animal
Male
Melatonin
Naloxone
Pineal Gland
Rats
Rats, Inbred Strains
Support, Non-U.S. Gov't
spellingShingle Endogenous opioids
Melatonin
Naloxone
Norepinephrine
Pineal gland
endorphin
melatonin
naloxone
neurotransmitter
noradrenalin
radioisotope
animal experiment
central nervous system
endocrine system
nervous system
nonhuman
noradrenalin h 3
photoperiodicity
pineal body
rat
subcutaneous drug administration
synapse
Animal
Male
Melatonin
Naloxone
Pineal Gland
Rats
Rats, Inbred Strains
Support, Non-U.S. Gov't
Effect of naloxone on the nocturnal rise of rat pineal melatonin content
topic_facet Endogenous opioids
Melatonin
Naloxone
Norepinephrine
Pineal gland
endorphin
melatonin
naloxone
neurotransmitter
noradrenalin
radioisotope
animal experiment
central nervous system
endocrine system
nervous system
nonhuman
noradrenalin h 3
photoperiodicity
pineal body
rat
subcutaneous drug administration
synapse
Animal
Male
Melatonin
Naloxone
Pineal Gland
Rats
Rats, Inbred Strains
Support, Non-U.S. Gov't
description Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-4M) did not affect either in vitro rat pineal melatonin content or 3H-labeled transmitter release in glands previously incubated with [3H]norepinephrine. Hence a central, rather than a peripheral opioid synapse appears to be involved in naloxone effect on nocturnal melatonin increase. © 1984.
title Effect of naloxone on the nocturnal rise of rat pineal melatonin content
title_short Effect of naloxone on the nocturnal rise of rat pineal melatonin content
title_full Effect of naloxone on the nocturnal rise of rat pineal melatonin content
title_fullStr Effect of naloxone on the nocturnal rise of rat pineal melatonin content
title_full_unstemmed Effect of naloxone on the nocturnal rise of rat pineal melatonin content
title_sort effect of naloxone on the nocturnal rise of rat pineal melatonin content
publishDate 1984
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v98_n2_p261_Lowenstein
http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein
_version_ 1768541640703606784