Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations

Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support...

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Detalles Bibliográficos
Publicado: 1980
Materias:
Medial basal hypothalamus
Melatonin
Prostaglandins
melatonin
prostaglandin E
animal
article
drug effect
hypothalamus
in vitro study
male
metabolism
rat
Animals
Hypothalamus
Hypothalamus, Middle
Male
Prostaglandins E
Rats
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v67_n1_p151_Cardinali
http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_00142999_v67_n1_p151_Cardinali
record_format dspace
spelling paper:paper_00142999_v67_n1_p151_Cardinali2023-06-08T14:36:54Z Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Melatonin Prostaglandins E Rats Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support the view that melatonin is a physiological inhibitor of PG synthesis in MBH. © 1980, All rights reserved. 1980 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v67_n1_p151_Cardinali http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Medial basal hypothalamus
Melatonin
Prostaglandins
melatonin
prostaglandin E
animal
article
drug effect
hypothalamus
in vitro study
male
metabolism
rat
Animals
Hypothalamus
Hypothalamus, Middle
Male
Melatonin
Prostaglandins E
Rats
spellingShingle Medial basal hypothalamus
Melatonin
Prostaglandins
melatonin
prostaglandin E
animal
article
drug effect
hypothalamus
in vitro study
male
metabolism
rat
Animals
Hypothalamus
Hypothalamus, Middle
Male
Melatonin
Prostaglandins E
Rats
Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
topic_facet Medial basal hypothalamus
Melatonin
Prostaglandins
melatonin
prostaglandin E
animal
article
drug effect
hypothalamus
in vitro study
male
metabolism
rat
Animals
Hypothalamus
Hypothalamus, Middle
Male
Melatonin
Prostaglandins E
Rats
description Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support the view that melatonin is a physiological inhibitor of PG synthesis in MBH. © 1980, All rights reserved.
title Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_short Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_full Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_fullStr Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_full_unstemmed Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_sort prostaglandin e release by rat medial basal hypothalamus in vitro. inhibition by melatonin at submicromolar concentrations
publishDate 1980
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v67_n1_p151_Cardinali
http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
_version_ 1768542439929282560

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