Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids

Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The m...

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Autor principal:	Muchnik de Lederkremer, Rosa María
Publicado:	1977
Materias:	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid glucosamine lignoceric acid myristic acid palmitic acid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v74_n2_p263_DELEDERKREMER http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00142956_v74_n2_p263_DELEDERKREMER
record_format	dspace
spelling	paper:paper_00142956_v74_n2_p263_DELEDERKREMER2023-06-08T14:36:45Z Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids Muchnik de Lederkremer, Rosa María amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The main fatty acids are palmitic (6.9%) and lignoceric (4.6%) acids. Stearic (0.55%), oleic (0.15%) and myristic (0.18%) acids were also found. One third of the fatty acids are bound in the lipopeptidophosphoglycan as esters (14 mmol%) and two thirds as amides (28 mmol%). Lignoceric acid was found to be bound only as amide. Two ninhydrin‐positive compounds, obtained by chloroform extraction of a total acid hydrolysate of the lipopeptidophosphoglycan, were tentatively identified as sphingosine bases. Copyright © 1977, Wiley Blackwell. All rights reserved Fil:DE LEDERKREMER, R.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1977 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v74_n2_p263_DELEDERKREMER http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi
spellingShingle	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi Muchnik de Lederkremer, Rosa María Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
topic_facet	amide carbohydrate drug derivative fatty acid hydroxylamine organophosphorus compound peptidoglycan phospholipid fatty acid glucosamine lignoceric acid myristic acid palmitic acid peptidoglycan phospholipid sphingosine stearic acid animal article gas chromatography isolation and purification polyacrylamide gel electrophoresis Trypanosoma cruzi cell membrane glycan phosphate lipoprotein in vitro study microorganism theoretical study trypanosoma cruzi Amides Animal Carbohydrates Chromatography, Gas Electrophoresis, Polyacrylamide Gel Fatty Acids Hydroxylamines Organophosphorus Compounds Peptidoglycan Phospholipids Trypanosoma cruzi
description	Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The main fatty acids are palmitic (6.9%) and lignoceric (4.6%) acids. Stearic (0.55%), oleic (0.15%) and myristic (0.18%) acids were also found. One third of the fatty acids are bound in the lipopeptidophosphoglycan as esters (14 mmol%) and two thirds as amides (28 mmol%). Lignoceric acid was found to be bound only as amide. Two ninhydrin‐positive compounds, obtained by chloroform extraction of a total acid hydrolysate of the lipopeptidophosphoglycan, were tentatively identified as sphingosine bases. Copyright © 1977, Wiley Blackwell. All rights reserved
author	Muchnik de Lederkremer, Rosa María
author_facet	Muchnik de Lederkremer, Rosa María
author_sort	Muchnik de Lederkremer, Rosa María
title	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_short	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_full	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_fullStr	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_full_unstemmed	Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
title_sort	lipopeptidophosphoglycan from trypanosoma cruzi amide and ester‐linked fatty acids
publishDate	1977
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v74_n2_p263_DELEDERKREMER http://hdl.handle.net/20.500.12110/paper_00142956_v74_n2_p263_DELEDERKREMER
work_keys_str_mv	AT muchnikdelederkremerrosamaria lipopeptidophosphoglycanfromtrypanosomacruziamideandesterlinkedfattyacids
_version_	1768546097653874688

Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids

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