Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi

The structure of the carbohydrate moiety of the lipopeptidophosphoglycan from Trypanosoma cruzi was studied by 13C NMR spectroscopy and by methylation analysis of the original and of an acid‐degraded sample. An oligosaccharide, consisting of 2‐O‐substituted and 6‐O‐substituted mannoses, which is lin...

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Autores principales:	Muchnik de Lederkremer, Rosa María, Casal de Russo, Olga Liliana, Couto, Alicia Susana
Publicado:	1985
Materias:	animal cell biochemistry cytology epimastigote glycan phosphate lipoprotein nonhuman priority journal protozoon trypanosoma cruzi Animal Chemistry Glycosides Hydrolysis Magnetic Resonance Spectroscopy Methylation Oligosaccharides Optical Rotation Peptidoglycan Phospholipids Ribose Support, Non-U.S. Gov't Trypanosoma cruzi
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v151_n3_p539_DeLederkremer http://hdl.handle.net/20.500.12110/paper_00142956_v151_n3_p539_DeLederkremer
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00142956_v151_n3_p539_DeLederkremer
record_format	dspace
spelling	paper:paper_00142956_v151_n3_p539_DeLederkremer2023-06-08T14:36:38Z Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi Muchnik de Lederkremer, Rosa María Casal de Russo, Olga Liliana Couto, Alicia Susana animal cell biochemistry cytology epimastigote glycan phosphate lipoprotein nonhuman priority journal protozoon trypanosoma cruzi Animal Chemistry Glycosides Hydrolysis Magnetic Resonance Spectroscopy Methylation Oligosaccharides Optical Rotation Peptidoglycan Phospholipids Ribose Support, Non-U.S. Gov't Trypanosoma cruzi The structure of the carbohydrate moiety of the lipopeptidophosphoglycan from Trypanosoma cruzi was studied by 13C NMR spectroscopy and by methylation analysis of the original and of an acid‐degraded sample. An oligosaccharide, consisting of 2‐O‐substituted and 6‐O‐substituted mannoses, which is linked to the ceramide, was separated by partial acid hydrolysis from an external chain that contained 3‐O‐substituted mannopyranosyl residues. β‐D‐Galactofuranosyl terminal units are attached to position 3 of (1 → 2)‐linked mannopyranose. Besides the previously reported monosaccharide components (mannose, galactose, glucose and glucosamine), ribose was identified in a partial acid hydrolysate of the lipopeptidophosphoglycan. The last three sugars are minor components and their oganization into the overall structure of the lipopeptidophosphoglycan has not been determined. Copyright © 1985, Wiley Blackwell. All rights reserved Fil:De Lederkremer, R.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Casal, O.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Couto, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1985 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v151_n3_p539_DeLederkremer http://hdl.handle.net/20.500.12110/paper_00142956_v151_n3_p539_DeLederkremer
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	animal cell biochemistry cytology epimastigote glycan phosphate lipoprotein nonhuman priority journal protozoon trypanosoma cruzi Animal Chemistry Glycosides Hydrolysis Magnetic Resonance Spectroscopy Methylation Oligosaccharides Optical Rotation Peptidoglycan Phospholipids Ribose Support, Non-U.S. Gov't Trypanosoma cruzi
spellingShingle	animal cell biochemistry cytology epimastigote glycan phosphate lipoprotein nonhuman priority journal protozoon trypanosoma cruzi Animal Chemistry Glycosides Hydrolysis Magnetic Resonance Spectroscopy Methylation Oligosaccharides Optical Rotation Peptidoglycan Phospholipids Ribose Support, Non-U.S. Gov't Trypanosoma cruzi Muchnik de Lederkremer, Rosa María Casal de Russo, Olga Liliana Couto, Alicia Susana Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
topic_facet	animal cell biochemistry cytology epimastigote glycan phosphate lipoprotein nonhuman priority journal protozoon trypanosoma cruzi Animal Chemistry Glycosides Hydrolysis Magnetic Resonance Spectroscopy Methylation Oligosaccharides Optical Rotation Peptidoglycan Phospholipids Ribose Support, Non-U.S. Gov't Trypanosoma cruzi
description	The structure of the carbohydrate moiety of the lipopeptidophosphoglycan from Trypanosoma cruzi was studied by 13C NMR spectroscopy and by methylation analysis of the original and of an acid‐degraded sample. An oligosaccharide, consisting of 2‐O‐substituted and 6‐O‐substituted mannoses, which is linked to the ceramide, was separated by partial acid hydrolysis from an external chain that contained 3‐O‐substituted mannopyranosyl residues. β‐D‐Galactofuranosyl terminal units are attached to position 3 of (1 → 2)‐linked mannopyranose. Besides the previously reported monosaccharide components (mannose, galactose, glucose and glucosamine), ribose was identified in a partial acid hydrolysate of the lipopeptidophosphoglycan. The last three sugars are minor components and their oganization into the overall structure of the lipopeptidophosphoglycan has not been determined. Copyright © 1985, Wiley Blackwell. All rights reserved
author	Muchnik de Lederkremer, Rosa María Casal de Russo, Olga Liliana Couto, Alicia Susana
author_facet	Muchnik de Lederkremer, Rosa María Casal de Russo, Olga Liliana Couto, Alicia Susana
author_sort	Muchnik de Lederkremer, Rosa María
title	Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
title_short	Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
title_full	Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
title_fullStr	Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
title_full_unstemmed	Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi
title_sort	structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from trypanosoma cruzi
publishDate	1985
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v151_n3_p539_DeLederkremer http://hdl.handle.net/20.500.12110/paper_00142956_v151_n3_p539_DeLederkremer
work_keys_str_mv	AT muchnikdelederkremerrosamaria structuralstudiesontheoligosaccharidemoetyofthelipopeptidophosphoglycanfromtrypanosomacruzi AT casalderussoolgaliliana structuralstudiesontheoligosaccharidemoetyofthelipopeptidophosphoglycanfromtrypanosomacruzi AT coutoaliciasusana structuralstudiesontheoligosaccharidemoetyofthelipopeptidophosphoglycanfromtrypanosomacruzi
_version_	1768543212028297216

Structural studies on the oligosaccharide moety of the lipopeptidophosphoglycan from Trypanosoma cruzi

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