The initation of glycogen biosynthesis in rat heart

A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of g...

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Detalles Bibliográficos
Publicado: 1983
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pH
rat
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v135_n1_p175_BLUMENFELD
http://hdl.handle.net/20.500.12110/paper_00142956_v135_n1_p175_BLUMENFELD
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spelling paper:paper_00142956_v135_n1_p175_BLUMENFELD2023-06-08T14:36:37Z The initation of glycogen biosynthesis in rat heart glycogen trichloroacetic acid uridine diphosphate glucose animal article biosynthesis heart muscle kinetics metabolism pH precipitation rat rat strain RNA translation solubility Animal Glycogen Hydrogen-Ion Concentration Kinetics Myocardium Peptide Chain Initiation Precipitation Rats Rats, Inbred Strains Solubility Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Trichloroacetic Acid Uridine Diphosphate Glucose A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of glycogen synthesis occurs by apposition of glucose residues to a protein and that the material so synthesized in vitro corresponds to the protein‐bound glycogen reported to exist in rat heart. The ability to label the putative protein primer in vitro with [14C]glucose should assist the isolation of the primer and the elucidation of the nature of the association between the carbohydrate and protein moeities. Copyright © 1983, Wiley Blackwell. All rights reserved 1983 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v135_n1_p175_BLUMENFELD http://hdl.handle.net/20.500.12110/paper_00142956_v135_n1_p175_BLUMENFELD
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic glycogen
trichloroacetic acid
uridine diphosphate glucose
animal
article
biosynthesis
heart muscle
kinetics
metabolism
pH
precipitation
rat
rat strain
RNA translation
solubility
Animal
Glycogen
Hydrogen-Ion Concentration
Kinetics
Myocardium
Peptide Chain Initiation
Precipitation
Rats
Rats, Inbred Strains
Solubility
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.
Trichloroacetic Acid
Uridine Diphosphate Glucose
spellingShingle glycogen
trichloroacetic acid
uridine diphosphate glucose
animal
article
biosynthesis
heart muscle
kinetics
metabolism
pH
precipitation
rat
rat strain
RNA translation
solubility
Animal
Glycogen
Hydrogen-Ion Concentration
Kinetics
Myocardium
Peptide Chain Initiation
Precipitation
Rats
Rats, Inbred Strains
Solubility
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.
Trichloroacetic Acid
Uridine Diphosphate Glucose
The initation of glycogen biosynthesis in rat heart
topic_facet glycogen
trichloroacetic acid
uridine diphosphate glucose
animal
article
biosynthesis
heart muscle
kinetics
metabolism
pH
precipitation
rat
rat strain
RNA translation
solubility
Animal
Glycogen
Hydrogen-Ion Concentration
Kinetics
Myocardium
Peptide Chain Initiation
Precipitation
Rats
Rats, Inbred Strains
Solubility
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.
Trichloroacetic Acid
Uridine Diphosphate Glucose
description A rat heart extract synthesizes glycogen‐like material from UDP‐glucose in the absence of added primer. Most of this material is precipitable by dilute trichloroacetic acid, in contrast to glycogen synthesized in presence of added glycogen primer. It is postulated that the endogenous initiation of glycogen synthesis occurs by apposition of glucose residues to a protein and that the material so synthesized in vitro corresponds to the protein‐bound glycogen reported to exist in rat heart. The ability to label the putative protein primer in vitro with [14C]glucose should assist the isolation of the primer and the elucidation of the nature of the association between the carbohydrate and protein moeities. Copyright © 1983, Wiley Blackwell. All rights reserved
title The initation of glycogen biosynthesis in rat heart
title_short The initation of glycogen biosynthesis in rat heart
title_full The initation of glycogen biosynthesis in rat heart
title_fullStr The initation of glycogen biosynthesis in rat heart
title_full_unstemmed The initation of glycogen biosynthesis in rat heart
title_sort initation of glycogen biosynthesis in rat heart
publishDate 1983
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v135_n1_p175_BLUMENFELD
http://hdl.handle.net/20.500.12110/paper_00142956_v135_n1_p175_BLUMENFELD
_version_ 1768542391788109824