Active and total transforming growth factor-β1 are differentially regulated by dopamine and estradiol in the pituitary

Dopamine, acting through the dopamine type 2 receptor (Drd2), is the main inhibitor of pituitary prolactin (PRL) secretion and lactotroph proliferation. TGF-β1 is involved, at least in part, in mediating these actions. It was described that TGF-β1 synthesis in rat pituitary lactotrophs is up-regulat...

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Detalles Bibliográficos
Publicado:	2011
Materias:	dopamine dopamine 2 receptor estradiol messenger RNA prolactin sulpiride transforming growth factor beta1 transforming growth factor beta2 allele animal cell animal experiment article cell proliferation female hypophysis hypophysis cell in vitro study in vivo study mouse nonhuman priority journal prolactin secreting cell Animals Cell Proliferation Cells, Cultured Dopamine Agonists Dopamine Antagonists Estradiol Female Gene Expression Regulation Hyperprolactinemia Lactotrophs Mice Mice, 129 Strain Mice, Inbred C57BL Mice, Transgenic Pituitary Gland, Anterior Prolactin Protein-Serine-Threonine Kinases Receptors, Dopamine D2 Receptors, Transforming Growth Factor beta RNA, Messenger Transforming Growth Factor beta1
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00137227_v152_n7_p2722_Recouvreux http://hdl.handle.net/20.500.12110/paper_00137227_v152_n7_p2722_Recouvreux
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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