Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution

Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods:...

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Publicado: 2004
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00099120_v37_n5_p404_Bianchi
http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi
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spelling paper:paper_00099120_v37_n5_p404_Bianchi2023-06-08T14:34:10Z Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution Biochemical markers Postoperative evolution C reactive protein lactic acid adult aged article chemical parameters controlled study early diagnosis female gastrointestinal surgery human major clinical study male microalbuminuria postoperative complication preoperative evaluation priority journal statistical significance Acid-Base Imbalance Adult Aged Albuminuria Argentina Biological Markers C-Reactive Protein Creatinine Digestive System Surgical Procedures Female Humans Lactic Acid Male Middle Aged Postoperative Complications Postoperative Period Predictive Value of Tests Prospective Studies Systemic Inflammatory Response Syndrome Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved. 2004 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00099120_v37_n5_p404_Bianchi http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Biochemical markers
Postoperative evolution
C reactive protein
lactic acid
adult
aged
article
chemical parameters
controlled study
early diagnosis
female
gastrointestinal surgery
human
major clinical study
male
microalbuminuria
postoperative complication
preoperative evaluation
priority journal
statistical significance
Acid-Base Imbalance
Adult
Aged
Albuminuria
Argentina
Biological Markers
C-Reactive Protein
Creatinine
Digestive System Surgical Procedures
Female
Humans
Lactic Acid
Male
Middle Aged
Postoperative Complications
Postoperative Period
Predictive Value of Tests
Prospective Studies
Systemic Inflammatory Response Syndrome
spellingShingle Biochemical markers
Postoperative evolution
C reactive protein
lactic acid
adult
aged
article
chemical parameters
controlled study
early diagnosis
female
gastrointestinal surgery
human
major clinical study
male
microalbuminuria
postoperative complication
preoperative evaluation
priority journal
statistical significance
Acid-Base Imbalance
Adult
Aged
Albuminuria
Argentina
Biological Markers
C-Reactive Protein
Creatinine
Digestive System Surgical Procedures
Female
Humans
Lactic Acid
Male
Middle Aged
Postoperative Complications
Postoperative Period
Predictive Value of Tests
Prospective Studies
Systemic Inflammatory Response Syndrome
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
topic_facet Biochemical markers
Postoperative evolution
C reactive protein
lactic acid
adult
aged
article
chemical parameters
controlled study
early diagnosis
female
gastrointestinal surgery
human
major clinical study
male
microalbuminuria
postoperative complication
preoperative evaluation
priority journal
statistical significance
Acid-Base Imbalance
Adult
Aged
Albuminuria
Argentina
Biological Markers
C-Reactive Protein
Creatinine
Digestive System Surgical Procedures
Female
Humans
Lactic Acid
Male
Middle Aged
Postoperative Complications
Postoperative Period
Predictive Value of Tests
Prospective Studies
Systemic Inflammatory Response Syndrome
description Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved.
title Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
title_short Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
title_full Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
title_fullStr Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
title_full_unstemmed Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
title_sort utility of base deficit, lactic acid, microalbuminuria, and c-reactive protein in the early detection of complications in the immediate postoperative evolution
publishDate 2004
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00099120_v37_n5_p404_Bianchi
http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi
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