Electric field effects on the reactivity of heme model systems

Proteins integrated or transiently bound to membranes are subject to strong electric fields. However, the role of these fields on tuning the reactivity of redox proteins is still an open issue. High electric fields are also present in protein-based electrochemical devices. In this work we report DFT...

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Detalles Bibliográficos
Autores principales:	De Biase, Pablo Martín, Doctorovich, Fabio Ariel, Murgida, Daniel Horacio, Estrin, Dario Ariel
Publicado:	2007
Materias:	Electric field effects Electrochemistry Porphyrins Proteins Redox reactions Heme proteins Ligand binding Redox proteins Pigments
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00092614_v434_n1-3_p121_DeBiase http://hdl.handle.net/20.500.12110/paper_00092614_v434_n1-3_p121_DeBiase
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00092614_v434_n1-3_p121_DeBiase
record_format	dspace
spelling	paper:paper_00092614_v434_n1-3_p121_DeBiase2023-06-08T14:33:49Z Electric field effects on the reactivity of heme model systems De Biase, Pablo Martín Doctorovich, Fabio Ariel Murgida, Daniel Horacio Estrin, Dario Ariel Electric field effects Electrochemistry Porphyrins Proteins Redox reactions Heme proteins Ligand binding Redox proteins Pigments Proteins integrated or transiently bound to membranes are subject to strong electric fields. However, the role of these fields on tuning the reactivity of redox proteins is still an open issue. High electric fields are also present in protein-based electrochemical devices. In this work we report DFT calculations of the electric field effects on ligand binding and on the redox potentials of porphyrin models representing the active sites of typical heme proteins such as cytochrome c, cytochrome c oxidase, cytochrome c peroxidase and cytochrome P450. © 2006 Elsevier B.V. All rights reserved. Fil:De Biase, P.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Doctorovich, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Murgida, D.H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Estrin, D.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2007 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00092614_v434_n1-3_p121_DeBiase http://hdl.handle.net/20.500.12110/paper_00092614_v434_n1-3_p121_DeBiase
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Electric field effects Electrochemistry Porphyrins Proteins Redox reactions Heme proteins Ligand binding Redox proteins Pigments
spellingShingle	Electric field effects Electrochemistry Porphyrins Proteins Redox reactions Heme proteins Ligand binding Redox proteins Pigments De Biase, Pablo Martín Doctorovich, Fabio Ariel Murgida, Daniel Horacio Estrin, Dario Ariel Electric field effects on the reactivity of heme model systems
topic_facet	Electric field effects Electrochemistry Porphyrins Proteins Redox reactions Heme proteins Ligand binding Redox proteins Pigments
description	Proteins integrated or transiently bound to membranes are subject to strong electric fields. However, the role of these fields on tuning the reactivity of redox proteins is still an open issue. High electric fields are also present in protein-based electrochemical devices. In this work we report DFT calculations of the electric field effects on ligand binding and on the redox potentials of porphyrin models representing the active sites of typical heme proteins such as cytochrome c, cytochrome c oxidase, cytochrome c peroxidase and cytochrome P450. © 2006 Elsevier B.V. All rights reserved.
author	De Biase, Pablo Martín Doctorovich, Fabio Ariel Murgida, Daniel Horacio Estrin, Dario Ariel
author_facet	De Biase, Pablo Martín Doctorovich, Fabio Ariel Murgida, Daniel Horacio Estrin, Dario Ariel
author_sort	De Biase, Pablo Martín
title	Electric field effects on the reactivity of heme model systems
title_short	Electric field effects on the reactivity of heme model systems
title_full	Electric field effects on the reactivity of heme model systems
title_fullStr	Electric field effects on the reactivity of heme model systems
title_full_unstemmed	Electric field effects on the reactivity of heme model systems
title_sort	electric field effects on the reactivity of heme model systems
publishDate	2007
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00092614_v434_n1-3_p121_DeBiase http://hdl.handle.net/20.500.12110/paper_00092614_v434_n1-3_p121_DeBiase
work_keys_str_mv	AT debiasepablomartin electricfieldeffectsonthereactivityofhememodelsystems AT doctorovichfabioariel electricfieldeffectsonthereactivityofhememodelsystems AT murgidadanielhoracio electricfieldeffectsonthereactivityofhememodelsystems AT estrindarioariel electricfieldeffectsonthereactivityofhememodelsystems
_version_	1768544577437827072

Electric field effects on the reactivity of heme model systems

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