Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles
Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experime...
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2002
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n24_p2419_Fascio http://hdl.handle.net/20.500.12110/paper_00086215_v337_n24_p2419_Fascio |
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paper:paper_00086215_v337_n24_p2419_Fascio |
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paper:paper_00086215_v337_n24_p2419_Fascio2023-06-08T14:32:43Z Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles Intramolecular 1,3-dipolar cycloaddition Isoxazolines Stereocontrol, NMR spectroscopy X-Ray crystallography Addition reactions Nuclear magnetic resonance spectroscopy Stereochemistry Synthesis (chemical) X ray diffraction analysis Chiral centers Carbohydrates isoxazoline derivative fused heterocyclic rings isoxazole derivative article carbon nuclear magnetic resonance crystal structure cycloaddition drug synthesis nuclear Overhauser effect priority journal proton nuclear magnetic resonance X ray diffraction chemistry nuclear magnetic resonance stereoisomerism synthesis X ray crystallography Crystallography, X-Ray Heterocyclic Compounds with 4 or More Rings Isoxazoles Nuclear Magnetic Resonance, Biomolecular Stereoisomerism Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved. 2002 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n24_p2419_Fascio http://hdl.handle.net/20.500.12110/paper_00086215_v337_n24_p2419_Fascio |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Intramolecular 1,3-dipolar cycloaddition Isoxazolines Stereocontrol, NMR spectroscopy X-Ray crystallography Addition reactions Nuclear magnetic resonance spectroscopy Stereochemistry Synthesis (chemical) X ray diffraction analysis Chiral centers Carbohydrates isoxazoline derivative fused heterocyclic rings isoxazole derivative article carbon nuclear magnetic resonance crystal structure cycloaddition drug synthesis nuclear Overhauser effect priority journal proton nuclear magnetic resonance X ray diffraction chemistry nuclear magnetic resonance stereoisomerism synthesis X ray crystallography Crystallography, X-Ray Heterocyclic Compounds with 4 or More Rings Isoxazoles Nuclear Magnetic Resonance, Biomolecular Stereoisomerism |
| spellingShingle |
Intramolecular 1,3-dipolar cycloaddition Isoxazolines Stereocontrol, NMR spectroscopy X-Ray crystallography Addition reactions Nuclear magnetic resonance spectroscopy Stereochemistry Synthesis (chemical) X ray diffraction analysis Chiral centers Carbohydrates isoxazoline derivative fused heterocyclic rings isoxazole derivative article carbon nuclear magnetic resonance crystal structure cycloaddition drug synthesis nuclear Overhauser effect priority journal proton nuclear magnetic resonance X ray diffraction chemistry nuclear magnetic resonance stereoisomerism synthesis X ray crystallography Crystallography, X-Ray Heterocyclic Compounds with 4 or More Rings Isoxazoles Nuclear Magnetic Resonance, Biomolecular Stereoisomerism Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| topic_facet |
Intramolecular 1,3-dipolar cycloaddition Isoxazolines Stereocontrol, NMR spectroscopy X-Ray crystallography Addition reactions Nuclear magnetic resonance spectroscopy Stereochemistry Synthesis (chemical) X ray diffraction analysis Chiral centers Carbohydrates isoxazoline derivative fused heterocyclic rings isoxazole derivative article carbon nuclear magnetic resonance crystal structure cycloaddition drug synthesis nuclear Overhauser effect priority journal proton nuclear magnetic resonance X ray diffraction chemistry nuclear magnetic resonance stereoisomerism synthesis X ray crystallography Crystallography, X-Ray Heterocyclic Compounds with 4 or More Rings Isoxazoles Nuclear Magnetic Resonance, Biomolecular Stereoisomerism |
| description |
Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved. |
| title |
Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| title_short |
Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| title_full |
Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| title_fullStr |
Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| title_full_unstemmed |
Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles |
| title_sort |
synthesis, high-resolution nmr spectroscopic analysis, and single-crystal x-ray diffraction of isoxazoline tetracycles |
| publishDate |
2002 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n24_p2419_Fascio http://hdl.handle.net/20.500.12110/paper_00086215_v337_n24_p2419_Fascio |
| _version_ |
1768542345141157888 |