Facile synthesis of glycofuranosyl isothiocyanates

Peracylated glycofuranosyl isothiocyanates are obtained under smooth conditions starting from the corresponding glycosyl chloride by reaction with potassium thiocyanate in anhydrous acetone at room temperature, classical conditions for the synthesis of glycopyranosyl thiocyanates. In the case of fur...

Descripción completa

Guardado en:

Detalles Bibliográficos
Publicado:	1997
Materias:	Glycofuranosylisothiocyanates Glycofuranosylthiourethanes carbohydrate derivative isothiocyanic acid derivative article carbohydrate synthesis drug synthesis in vitro study priority journal reaction analysis stereochemistry
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v304_n3-4_p257_Marino http://hdl.handle.net/20.500.12110/paper_00086215_v304_n3-4_p257_Marino
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00086215_v304_n3-4_p257_Marino
record_format	dspace
spelling	paper:paper_00086215_v304_n3-4_p257_Marino2023-06-08T14:32:36Z Facile synthesis of glycofuranosyl isothiocyanates Glycofuranosylisothiocyanates Glycofuranosylthiourethanes carbohydrate derivative isothiocyanic acid derivative article carbohydrate synthesis drug synthesis in vitro study priority journal reaction analysis stereochemistry Peracylated glycofuranosyl isothiocyanates are obtained under smooth conditions starting from the corresponding glycosyl chloride by reaction with potassium thiocyanate in anhydrous acetone at room temperature, classical conditions for the synthesis of glycopyranosyl thiocyanates. In the case of furanoses, no glycosyl thiocyanates are obtained, and the procedure leads to the 1,2-trans isothiocyanates, stereoselectively, with over 80% yield. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v304_n3-4_p257_Marino http://hdl.handle.net/20.500.12110/paper_00086215_v304_n3-4_p257_Marino
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Glycofuranosylisothiocyanates Glycofuranosylthiourethanes carbohydrate derivative isothiocyanic acid derivative article carbohydrate synthesis drug synthesis in vitro study priority journal reaction analysis stereochemistry
spellingShingle	Glycofuranosylisothiocyanates Glycofuranosylthiourethanes carbohydrate derivative isothiocyanic acid derivative article carbohydrate synthesis drug synthesis in vitro study priority journal reaction analysis stereochemistry Facile synthesis of glycofuranosyl isothiocyanates
topic_facet	Glycofuranosylisothiocyanates Glycofuranosylthiourethanes carbohydrate derivative isothiocyanic acid derivative article carbohydrate synthesis drug synthesis in vitro study priority journal reaction analysis stereochemistry
description	Peracylated glycofuranosyl isothiocyanates are obtained under smooth conditions starting from the corresponding glycosyl chloride by reaction with potassium thiocyanate in anhydrous acetone at room temperature, classical conditions for the synthesis of glycopyranosyl thiocyanates. In the case of furanoses, no glycosyl thiocyanates are obtained, and the procedure leads to the 1,2-trans isothiocyanates, stereoselectively, with over 80% yield.
title	Facile synthesis of glycofuranosyl isothiocyanates
title_short	Facile synthesis of glycofuranosyl isothiocyanates
title_full	Facile synthesis of glycofuranosyl isothiocyanates
title_fullStr	Facile synthesis of glycofuranosyl isothiocyanates
title_full_unstemmed	Facile synthesis of glycofuranosyl isothiocyanates
title_sort	facile synthesis of glycofuranosyl isothiocyanates
publishDate	1997
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v304_n3-4_p257_Marino http://hdl.handle.net/20.500.12110/paper_00086215_v304_n3-4_p257_Marino
_version_	1768544849192026112

Facile synthesis of glycofuranosyl isothiocyanates

Ejemplares similares