Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats

The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a sign...

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Publicado: 1982
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rat
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v241_n2_p366_Faigon
http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon
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spelling paper:paper_00068993_v241_n2_p366_Faigon2023-06-08T14:31:29Z Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats luteinizing hormone release melatonin pineal gland puberty estradiol gonadorelin luteinizing hormone melatonin progesterone animal experiment central nervous system endocrine system feedback system pineal body pinealectomy puberty rat subcutaneous drug administration Animal Estradiol Feedback Female Luteinizing Hormone Pineal Gland Progesterone Rats Rats, Inbred Strains Sex Maturation Support, Non-U.S. Gov't The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a significant LH release was found at day 22; Px rats showed a steroid-induced LH depression only at day 16, a positive feedback being detectable at day 20, 2 days earlier than in sham Px or intact rats. Daily injections of 10-50 μg melatonin to intact rats disrupted the LH negative feedback response at day 20, and diminished steroid-induced LH release at day 24. © 1982. 1982 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v241_n2_p366_Faigon http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic luteinizing hormone release
melatonin
pineal gland
puberty
estradiol
gonadorelin
luteinizing hormone
melatonin
progesterone
animal experiment
central nervous system
endocrine system
feedback system
pineal body
pinealectomy
puberty
rat
subcutaneous drug administration
Animal
Estradiol
Feedback
Female
Luteinizing Hormone
Pineal Gland
Progesterone
Rats
Rats, Inbred Strains
Sex Maturation
Support, Non-U.S. Gov't
spellingShingle luteinizing hormone release
melatonin
pineal gland
puberty
estradiol
gonadorelin
luteinizing hormone
melatonin
progesterone
animal experiment
central nervous system
endocrine system
feedback system
pineal body
pinealectomy
puberty
rat
subcutaneous drug administration
Animal
Estradiol
Feedback
Female
Luteinizing Hormone
Pineal Gland
Progesterone
Rats
Rats, Inbred Strains
Sex Maturation
Support, Non-U.S. Gov't
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
topic_facet luteinizing hormone release
melatonin
pineal gland
puberty
estradiol
gonadorelin
luteinizing hormone
melatonin
progesterone
animal experiment
central nervous system
endocrine system
feedback system
pineal body
pinealectomy
puberty
rat
subcutaneous drug administration
Animal
Estradiol
Feedback
Female
Luteinizing Hormone
Pineal Gland
Progesterone
Rats
Rats, Inbred Strains
Sex Maturation
Support, Non-U.S. Gov't
description The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a significant LH release was found at day 22; Px rats showed a steroid-induced LH depression only at day 16, a positive feedback being detectable at day 20, 2 days earlier than in sham Px or intact rats. Daily injections of 10-50 μg melatonin to intact rats disrupted the LH negative feedback response at day 20, and diminished steroid-induced LH release at day 24. © 1982.
title Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
title_short Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
title_full Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
title_fullStr Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
title_full_unstemmed Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
title_sort pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
publishDate 1982
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v241_n2_p366_Faigon
http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon
_version_ 1768542816710950912