Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period

Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained...

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Autores principales:	Soiza Reilly, Mariano, Fossati, Mariana, Azcurra, Julio Marcos
Publicado:	2004
Materias:	Basal ganglia Critical period D1 receptor D2 receptor Dopamine Motor plasticity Motor systems and sensorimotor integration Rat striatum dopamine 1 receptor dopamine 2 receptor isoprotein messenger RNA muscarinic receptor animal experiment animal tissue article binding site circling behavior controlled study corpus striatum learning male motor activity nonhuman ontogeny perinatal period priority journal protein binding protein expression rat synapse training Animals Corpus Striatum Critical Period (Psychology) Gene Expression Regulation Male Motor Activity Rats Rats, Sprague-Dawley Receptors, Dopamine D1 Receptors, Dopamine D2
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v1004_n1-2_p217_SoizaReilly http://hdl.handle.net/20.500.12110/paper_00068993_v1004_n1-2_p217_SoizaReilly
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00068993_v1004_n1-2_p217_SoizaReilly
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spelling	paper:paper_00068993_v1004_n1-2_p217_SoizaReilly2023-06-08T14:31:27Z Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period Soiza Reilly, Mariano Fossati, Mariana Azcurra, Julio Marcos Basal ganglia Critical period D1 receptor D2 receptor Dopamine Motor plasticity Motor systems and sensorimotor integration Rat striatum dopamine 1 receptor dopamine 2 receptor isoprotein messenger RNA muscarinic receptor animal experiment animal tissue article binding site circling behavior controlled study corpus striatum learning male motor activity nonhuman ontogeny perinatal period priority journal protein binding protein expression rat synapse training Animals Corpus Striatum Critical Period (Psychology) Gene Expression Regulation Male Motor Activity Rats Rats, Sprague-Dawley Receptors, Dopamine D1 Receptors, Dopamine D2 Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decrease of 40% in D2R binding sites (p<0.01) and of 45% in the D2R mRNA expression which involve short (p<0.05) and long (p<0.01) isoforms. In contrast, D1R binding sites nor its mRNA expression levels were affected by training, indicating a differential synaptic refinement during this ontogenetically fixed period. © 2004 Elsevier B.V. All rights reserved. Fil:Soiza-Reilly, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Fossati, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Azcurra, J.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2004 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v1004_n1-2_p217_SoizaReilly http://hdl.handle.net/20.500.12110/paper_00068993_v1004_n1-2_p217_SoizaReilly
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Basal ganglia Critical period D1 receptor D2 receptor Dopamine Motor plasticity Motor systems and sensorimotor integration Rat striatum dopamine 1 receptor dopamine 2 receptor isoprotein messenger RNA muscarinic receptor animal experiment animal tissue article binding site circling behavior controlled study corpus striatum learning male motor activity nonhuman ontogeny perinatal period priority journal protein binding protein expression rat synapse training Animals Corpus Striatum Critical Period (Psychology) Gene Expression Regulation Male Motor Activity Rats Rats, Sprague-Dawley Receptors, Dopamine D1 Receptors, Dopamine D2
spellingShingle	Basal ganglia Critical period D1 receptor D2 receptor Dopamine Motor plasticity Motor systems and sensorimotor integration Rat striatum dopamine 1 receptor dopamine 2 receptor isoprotein messenger RNA muscarinic receptor animal experiment animal tissue article binding site circling behavior controlled study corpus striatum learning male motor activity nonhuman ontogeny perinatal period priority journal protein binding protein expression rat synapse training Animals Corpus Striatum Critical Period (Psychology) Gene Expression Regulation Male Motor Activity Rats Rats, Sprague-Dawley Receptors, Dopamine D1 Receptors, Dopamine D2 Soiza Reilly, Mariano Fossati, Mariana Azcurra, Julio Marcos Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
topic_facet	Basal ganglia Critical period D1 receptor D2 receptor Dopamine Motor plasticity Motor systems and sensorimotor integration Rat striatum dopamine 1 receptor dopamine 2 receptor isoprotein messenger RNA muscarinic receptor animal experiment animal tissue article binding site circling behavior controlled study corpus striatum learning male motor activity nonhuman ontogeny perinatal period priority journal protein binding protein expression rat synapse training Animals Corpus Striatum Critical Period (Psychology) Gene Expression Regulation Male Motor Activity Rats Rats, Sprague-Dawley Receptors, Dopamine D1 Receptors, Dopamine D2
description	Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decrease of 40% in D2R binding sites (p<0.01) and of 45% in the D2R mRNA expression which involve short (p<0.05) and long (p<0.01) isoforms. In contrast, D1R binding sites nor its mRNA expression levels were affected by training, indicating a differential synaptic refinement during this ontogenetically fixed period. © 2004 Elsevier B.V. All rights reserved.
author	Soiza Reilly, Mariano Fossati, Mariana Azcurra, Julio Marcos
author_facet	Soiza Reilly, Mariano Fossati, Mariana Azcurra, Julio Marcos
author_sort	Soiza Reilly, Mariano
title	Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
title_short	Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
title_full	Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
title_fullStr	Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
title_full_unstemmed	Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period
title_sort	different dopamine d1 and d2 receptors expression after motor activity in the striatal critical period
publishDate	2004
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v1004_n1-2_p217_SoizaReilly http://hdl.handle.net/20.500.12110/paper_00068993_v1004_n1-2_p217_SoizaReilly
work_keys_str_mv	AT soizareillymariano differentdopamined1andd2receptorsexpressionaftermotoractivityinthestriatalcriticalperiod AT fossatimariana differentdopamined1andd2receptorsexpressionaftermotoractivityinthestriatalcriticalperiod AT azcurrajuliomarcos differentdopamined1andd2receptorsexpressionaftermotoractivityinthestriatalcriticalperiod
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Different dopamine D1 and D2 receptors expression after motor activity in the striatal critical period

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