Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems

Polypeptide synthesis programmed by poly(U) and globin mRNA has been studied in cell-free extracts from wheat germ. A two-step reaction with a preincubation at high Mg++ levels followed by a second step carried out after a shift to a low Mg++ concentration and the addition of labeled amino acids is...

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Publicado:	1980
Materias:	aurintricarboxylic acid globin magnesium messenger RNA polyuridylic acid article biosynthesis cell free system drug effect kinetics metabolism peptide synthesis plant protein synthesis wheat Aurintricarboxylic Acid Cell-Free System Globins Kinetics Magnesium Peptide Biosynthesis Plants Poly U Protein Biosynthesis RNA, Messenger Triticum
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291x_v96_n1_p54_Algranati http://hdl.handle.net/20.500.12110/paper_0006291x_v96_n1_p54_Algranati
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_0006291x_v96_n1_p54_Algranati
record_format	dspace
spelling	paper:paper_0006291x_v96_n1_p54_Algranati2023-06-08T14:30:28Z Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems aurintricarboxylic acid globin magnesium messenger RNA polyuridylic acid article biosynthesis cell free system drug effect kinetics metabolism peptide synthesis plant protein synthesis wheat Aurintricarboxylic Acid Cell-Free System Globins Kinetics Magnesium Peptide Biosynthesis Plants Poly U Protein Biosynthesis RNA, Messenger Triticum Polypeptide synthesis programmed by poly(U) and globin mRNA has been studied in cell-free extracts from wheat germ. A two-step reaction with a preincubation at high Mg++ levels followed by a second step carried out after a shift to a low Mg++ concentration and the addition of labeled amino acids is described. Under these conditions the initiation of polyphenylalanine synthesis can be blocked without affecting the elongation of polypeptide chains. This procedure allows the selective inhibition of polypeptide synthesis initiation without using any drug or antibiotic. © 1980, All rights reserved. 1980 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291x_v96_n1_p54_Algranati http://hdl.handle.net/20.500.12110/paper_0006291x_v96_n1_p54_Algranati
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	aurintricarboxylic acid globin magnesium messenger RNA polyuridylic acid article biosynthesis cell free system drug effect kinetics metabolism peptide synthesis plant protein synthesis wheat Aurintricarboxylic Acid Cell-Free System Globins Kinetics Magnesium Peptide Biosynthesis Plants Poly U Protein Biosynthesis RNA, Messenger Triticum
spellingShingle	aurintricarboxylic acid globin magnesium messenger RNA polyuridylic acid article biosynthesis cell free system drug effect kinetics metabolism peptide synthesis plant protein synthesis wheat Aurintricarboxylic Acid Cell-Free System Globins Kinetics Magnesium Peptide Biosynthesis Plants Poly U Protein Biosynthesis RNA, Messenger Triticum Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
topic_facet	aurintricarboxylic acid globin magnesium messenger RNA polyuridylic acid article biosynthesis cell free system drug effect kinetics metabolism peptide synthesis plant protein synthesis wheat Aurintricarboxylic Acid Cell-Free System Globins Kinetics Magnesium Peptide Biosynthesis Plants Poly U Protein Biosynthesis RNA, Messenger Triticum
description	Polypeptide synthesis programmed by poly(U) and globin mRNA has been studied in cell-free extracts from wheat germ. A two-step reaction with a preincubation at high Mg++ levels followed by a second step carried out after a shift to a low Mg++ concentration and the addition of labeled amino acids is described. Under these conditions the initiation of polyphenylalanine synthesis can be blocked without affecting the elongation of polypeptide chains. This procedure allows the selective inhibition of polypeptide synthesis initiation without using any drug or antibiotic. © 1980, All rights reserved.
title	Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
title_short	Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
title_full	Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
title_fullStr	Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
title_full_unstemmed	Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems
title_sort	inhibition of polypeptide synthesis initiation by a change of mg++ concentration in wheat germ cell-free systems
publishDate	1980
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291x_v96_n1_p54_Algranati http://hdl.handle.net/20.500.12110/paper_0006291x_v96_n1_p54_Algranati
_version_	1768544848286056448

Inhibition of polypeptide synthesis initiation by a change of Mg++ concentration in wheat germ cell-free systems

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