A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity

A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having t...

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Autores principales:	Flawiá, Mirtha María, Torres, Héctor Norberto
Publicado:	1974
Materias:	adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v58_n4_p990_Terenzi http://hdl.handle.net/20.500.12110/paper_0006291X_v58_n4_p990_Terenzi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_0006291X_v58_n4_p990_Terenzi
record_format	dspace
spelling	paper:paper_0006291X_v58_n4_p990_Terenzi2023-06-08T14:30:24Z A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity Flawiá, Mirtha María Torres, Héctor Norberto adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having the wild type allele yield isolates with the crisp phenotype all of them having low adenylate cyclase specific activity in crude extracts. The other phenotypes obtained showed wild type levels of specific activity. Addition of 3′, 5′ dibutyryl cyclic AMP to the FGSC No. 329 cultures increased four-fold mycelial growth rate and stimulated the formation of aerial hyphae. Simultaneously, uniform conidiation on the surface of the slant was inhibited by the cyclic AMP derivative. © 1974 Academic Press, Inc. Fil:Flawiá, M.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Torres, H.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1974 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v58_n4_p990_Terenzi http://hdl.handle.net/20.500.12110/paper_0006291X_v58_n4_p990_Terenzi
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity
spellingShingle	adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity Flawiá, Mirtha María Torres, Héctor Norberto A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
topic_facet	adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity
description	A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having the wild type allele yield isolates with the crisp phenotype all of them having low adenylate cyclase specific activity in crude extracts. The other phenotypes obtained showed wild type levels of specific activity. Addition of 3′, 5′ dibutyryl cyclic AMP to the FGSC No. 329 cultures increased four-fold mycelial growth rate and stimulated the formation of aerial hyphae. Simultaneously, uniform conidiation on the surface of the slant was inhibited by the cyclic AMP derivative. © 1974 Academic Press, Inc.
author	Flawiá, Mirtha María Torres, Héctor Norberto
author_facet	Flawiá, Mirtha María Torres, Héctor Norberto
author_sort	Flawiá, Mirtha María
title	A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
title_short	A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
title_full	A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
title_fullStr	A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
title_full_unstemmed	A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
title_sort	neurospora crassa morphological mutant showing reduced adenylate cyclase activity
publishDate	1974
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v58_n4_p990_Terenzi http://hdl.handle.net/20.500.12110/paper_0006291X_v58_n4_p990_Terenzi
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_version_	1768543589308039168

A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity

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