Mitoxantrone affects topoisomerase activities in human breast cancer cells
The effects of mitoxantrone, an antineoplastic DNA intercalator, on topoisomerase I and II were studied in two human breast cancer cell lines. A large increase of topoisomerase I activity was found when cells were exposed to various doses of mitoxantrone. Maximal effect was achieved with 20 and 40 n...
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1986
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v136_n2_p521_Crespi http://hdl.handle.net/20.500.12110/paper_0006291X_v136_n2_p521_Crespi |
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