The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine
The accumulation of argininosuccinate by an arg-10 mutant of Neurospora crassa is enhanced when growth-limiting amounts of arginine are used, or when citrulline is supplied in addition to non-limiting concentrations of arginine. Elevated levels of ornithine carbamoyl transferase (carbamoyl phosphate...
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1967
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00052787_v145_n1_p138_Nazario http://hdl.handle.net/20.500.12110/paper_00052787_v145_n1_p138_Nazario |
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paper:paper_00052787_v145_n1_p138_Nazario2023-06-08T14:29:57Z The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine arginine citrulline ornithine carbamoyltransferase article metabolism mutation Neurospora paper chromatography Arginine Chromatography, Paper Citrulline Mutation Neurospora Ornithine Carbamoyltransferase The accumulation of argininosuccinate by an arg-10 mutant of Neurospora crassa is enhanced when growth-limiting amounts of arginine are used, or when citrulline is supplied in addition to non-limiting concentrations of arginine. Elevated levels of ornithine carbamoyl transferase (carbamoyl phosphate: l-ornithine carbamoyl transferase, EC 2.1.3.3) are found under circumstances leading to accumulation of argininosuccinate. An explanation based on the possibility that citrulline might impose a limited availability of arginine has been excluded. Indeed, the mutant displays a higher mycelial pool of arginine, and an increased consumption of this amino acid when it is grown with added citrulline. It is emphasized that elevated (derepressed) levels of ornithine carbamoyl transferase prevail under these conditions. © 1967. 1967 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00052787_v145_n1_p138_Nazario http://hdl.handle.net/20.500.12110/paper_00052787_v145_n1_p138_Nazario |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
arginine citrulline ornithine carbamoyltransferase article metabolism mutation Neurospora paper chromatography Arginine Chromatography, Paper Citrulline Mutation Neurospora Ornithine Carbamoyltransferase |
spellingShingle |
arginine citrulline ornithine carbamoyltransferase article metabolism mutation Neurospora paper chromatography Arginine Chromatography, Paper Citrulline Mutation Neurospora Ornithine Carbamoyltransferase The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
topic_facet |
arginine citrulline ornithine carbamoyltransferase article metabolism mutation Neurospora paper chromatography Arginine Chromatography, Paper Citrulline Mutation Neurospora Ornithine Carbamoyltransferase |
description |
The accumulation of argininosuccinate by an arg-10 mutant of Neurospora crassa is enhanced when growth-limiting amounts of arginine are used, or when citrulline is supplied in addition to non-limiting concentrations of arginine. Elevated levels of ornithine carbamoyl transferase (carbamoyl phosphate: l-ornithine carbamoyl transferase, EC 2.1.3.3) are found under circumstances leading to accumulation of argininosuccinate. An explanation based on the possibility that citrulline might impose a limited availability of arginine has been excluded. Indeed, the mutant displays a higher mycelial pool of arginine, and an increased consumption of this amino acid when it is grown with added citrulline. It is emphasized that elevated (derepressed) levels of ornithine carbamoyl transferase prevail under these conditions. © 1967. |
title |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
title_short |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
title_full |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
title_fullStr |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
title_full_unstemmed |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine |
title_sort |
accumulation of argininosuccinate in neurospora crassa. i. elevated ornithine carbamoyl transferase with high concentrations of arginine |
publishDate |
1967 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00052787_v145_n1_p138_Nazario http://hdl.handle.net/20.500.12110/paper_00052787_v145_n1_p138_Nazario |
_version_ |
1768545490320752640 |