Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins

The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective m...

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Autores principales:	Martí, Marcelo Adrián, Bari, Sara Elizabeth, Estrin, Dario Ariel, Doctorovich, Fabio Ariel
Publicado:	2005
Materias:	Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Solubility Water
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00027863_v127_n13_p4680_Marti http://hdl.handle.net/20.500.12110/paper_00027863_v127_n13_p4680_Marti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00027863_v127_n13_p4680_Marti
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spelling	paper:paper_00027863_v127_n13_p4680_Marti2023-06-08T14:22:40Z Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins Martí, Marcelo Adrián Bari, Sara Elizabeth Estrin, Dario Ariel Doctorovich, Fabio Ariel Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective manner with concomitant formation of the {MnNO}7 complex (kon(HNO) ≈ 105 M-1 s-1), while they are inert or react very slowly with NO donors. DFT calculations and kinetic data suggest that HNO trapping is operative at least in the case of Mn IIITPPS, while catalytic decomposition of the HNO donors (sodium trioxodinitrate and toluene sulfohydroxamic acid) seems to be the main pathway for MnIIITEPyP. In the presence of oxygen, the product Mn IITEPyP(NO) oxidizes back to MnIIITEPyP, making it possible to process large ratios of nitroxyl donor with small amounts of porphyrin. © 2005 American Chemical Society. Fil:Martí, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Bari, S.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Estrin, D.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Doctorovich, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00027863_v127_n13_p4680_Marti http://hdl.handle.net/20.500.12110/paper_00027863_v127_n13_p4680_Marti
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water
spellingShingle	Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water Martí, Marcelo Adrián Bari, Sara Elizabeth Estrin, Dario Ariel Doctorovich, Fabio Ariel Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
topic_facet	Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water
description	The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective manner with concomitant formation of the {MnNO}7 complex (kon(HNO) ≈ 105 M-1 s-1), while they are inert or react very slowly with NO donors. DFT calculations and kinetic data suggest that HNO trapping is operative at least in the case of Mn IIITPPS, while catalytic decomposition of the HNO donors (sodium trioxodinitrate and toluene sulfohydroxamic acid) seems to be the main pathway for MnIIITEPyP. In the presence of oxygen, the product Mn IITEPyP(NO) oxidizes back to MnIIITEPyP, making it possible to process large ratios of nitroxyl donor with small amounts of porphyrin. © 2005 American Chemical Society.
author	Martí, Marcelo Adrián Bari, Sara Elizabeth Estrin, Dario Ariel Doctorovich, Fabio Ariel
author_facet	Martí, Marcelo Adrián Bari, Sara Elizabeth Estrin, Dario Ariel Doctorovich, Fabio Ariel
author_sort	Martí, Marcelo Adrián
title	Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
title_short	Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
title_full	Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
title_fullStr	Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
title_full_unstemmed	Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
title_sort	discrimination of nitroxyl and nitric oxide by water-soluble mn(iii) porphyrins
publishDate	2005
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00027863_v127_n13_p4680_Marti http://hdl.handle.net/20.500.12110/paper_00027863_v127_n13_p4680_Marti
work_keys_str_mv	AT martimarceloadrian discriminationofnitroxylandnitricoxidebywatersolublemniiiporphyrins AT barisaraelizabeth discriminationofnitroxylandnitricoxidebywatersolublemniiiporphyrins AT estrindarioariel discriminationofnitroxylandnitricoxidebywatersolublemniiiporphyrins AT doctorovichfabioariel discriminationofnitroxylandnitricoxidebywatersolublemniiiporphyrins
_version_	1768542199617683456

Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins

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