Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population

Fil: Celaya, Liliana Soledad. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.

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Autores principales: Celaya, Liliana Soledad, Viturro, Carmen Ines, Silva, Luis R.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: Sage Publications 2019
Materias:
Acantholippia salsoloides
β-thujone
Isoferulic acid
Cynaroside
Biological action
Acceso en línea:https://hdl.handle.net/20.500.12219/4967
Aporte de:
Repositorio Institucional Digital de la UNaM (RIDUNAM) de Universidad Nacional de Misiones
id I77-R195-20.500.12219-4967
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spelling I77-R195-20.500.12219-49672024-06-04T12:03:04Z Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population Celaya, Liliana Soledad Viturro, Carmen Ines Silva, Luis R. Acantholippia salsoloides β-thujone Isoferulic acid Cynaroside Biological action Fil: Celaya, Liliana Soledad. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina. Fil: Celaya, Liliana Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina. Fil: Celaya, Liliana Soledad. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Departamento de Ingeniería Química ; Argentina. Fil: Celaya, Liliana Soledad. Universidade do Porto. Faculdade de Farmácia. Laboratório de Farmacognosia; Portugal. Fil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina. Fil: Viturro, Carmen Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina. Fil: Silva, Luis R. Universidade da Beira Interior. Centro de Investigação em Ciências da Saúde; Portugal. Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine. A. salsoloides attributes its common name “rica-rica” to the fresh and sweet fragrance of the plant. In this work, 2 different polar extracts and the essential oil of a selected rica-rica population were studied. The phenolic composition was analyzed by high-performance liquid chromatography diode array detector; the essential oil profile was determined by gas-chromatography ion-trap mass spectrometry/flame ionization detection. For all extracts, the antibacterial potential was performed by in vitro assays; the antioxidant and α-glucosidase inhibition were determined in decoction and hydroethanolic extracts. The volatile profile allowed the identification of 26 volatile compounds, β-thujone (84%) being the major one in this rica-rica population. Eighteen phenolic compounds were identified; isoferulic acid (16%-18%) and cynaroside (45%-47%) were the larger ones. In a general way, the hydroethanolic extract was more active against Staphylococcus aureus and Micrococcus luteus (minimum inhibitory concentrations= 0.3- 1.3 mg/mL). Both polar extracts have strong antiradical activities although decoction extract proved to be more active against DPPH• (half-maximal inhibitory concentration [IC50] =36 μg/mL) and O2 ●−(IC50 =28 μg/mL) while hydroethanolic extract shows higher action over α-glucosidase (IC50 =217 μg/mL). The results suggest that A. salsoloides leaves and flowers may be an interesting source of natural antioxidants, antidiabetics, or antimicrobials, and could be used in dietary supplements, medicinal products and pharmaceutical formulations. 2019-06-25 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion https://hdl.handle.net/20.500.12219/4967 eng info:eu-repo/semantics/altIdentifier/hdl/http://hdl.handle.net/11336/105425 info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1177/1934578X19858542 info:eu-repo/semantics/altIdentifier/urn/http://journals.sagepub.com/doi/10.1177/1934578X19858542 info:eu-repo/semantics/openAccess application/pdf application/pdf 360 KB Sage Publications
institution Universidad Nacional de Misiones
institution_str I-77
repository_str R-195
collection Repositorio Institucional Digital de la UNaM (RIDUNAM)
language Inglés
topic Acantholippia salsoloides
β-thujone
Isoferulic acid
Cynaroside
Biological action
spellingShingle Acantholippia salsoloides
β-thujone
Isoferulic acid
Cynaroside
Biological action
Celaya, Liliana Soledad
Viturro, Carmen Ines
Silva, Luis R.
Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
topic_facet Acantholippia salsoloides
β-thujone
Isoferulic acid
Cynaroside
Biological action
description Fil: Celaya, Liliana Soledad. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.
format Artículo
Artículo
publishedVersion
author Celaya, Liliana Soledad
Viturro, Carmen Ines
Silva, Luis R.
author_facet Celaya, Liliana Soledad
Viturro, Carmen Ines
Silva, Luis R.
author_sort Celaya, Liliana Soledad
title Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
title_short Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
title_full Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
title_fullStr Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
title_full_unstemmed Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
title_sort acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population
publisher Sage Publications
publishDate 2019
url https://hdl.handle.net/20.500.12219/4967
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AT viturrocarmenines acantholippiasalsoloidesphytochemicalcompositionandbiologicalpotentialofathujonicpopulation
AT silvaluisr acantholippiasalsoloidesphytochemicalcompositionandbiologicalpotentialofathujonicpopulation
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