Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes

This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and...

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Autores principales: Asturias Arribas, Laura, Delfino, Mario Raúl, Alonso Lomillo, María Asunción, Domínguez Renedo, Olga
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley VCH Verlag 2021
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Acceso en línea:http://repositorio.unne.edu.ar/handle/123456789/28014
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spelling I48-R184-123456789-280142025-03-06T10:56:55Z Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes Asturias Arribas, Laura Delfino, Mario Raúl Alonso Lomillo, María Asunción Domínguez Renedo, Olga Nelfinavir Screen-printed electrode Electrochemical oxidation Carbon nanotubes This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC. 2021-06-01T21:35:23Z 2021-06-01T21:35:23Z 2016 Artículo Asturias Arribas, Laura, et.al., 2016. Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes. Electroanalysis. Weinheim: Wiley VCH Verlag, vol. 28, no. 9, p. 1-7. ISSN 1040-0397. 1040-0397 http://repositorio.unne.edu.ar/handle/123456789/28014 eng openAccess http://creativecommons.org/licenses/by-nc-nd/2.5/ar/ application/pdf application/pdf Wiley VCH Verlag Electroanalysis, 2016, vol. 28, no. 9, p. 1-7.
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-184
collection RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
language Inglés
topic Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
spellingShingle Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
Asturias Arribas, Laura
Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
topic_facet Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
description This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC.
format Artículo
author Asturias Arribas, Laura
Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
author_facet Asturias Arribas, Laura
Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
author_sort Asturias Arribas, Laura
title Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_short Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_full Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_fullStr Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_full_unstemmed Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_sort electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
publisher Wiley VCH Verlag
publishDate 2021
url http://repositorio.unne.edu.ar/handle/123456789/28014
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AT delfinomarioraul electrochemicaloxidationoftheantiretroviraldrugnelfinavironmodifiedscreenprintedelectrodes
AT alonsolomillomariaasuncion electrochemicaloxidationoftheantiretroviraldrugnelfinavironmodifiedscreenprintedelectrodes
AT dominguezrenedoolga electrochemicaloxidationoftheantiretroviraldrugnelfinavironmodifiedscreenprintedelectrodes
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