Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and...
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Wiley VCH Verlag
2021
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Acceso en línea: | http://repositorio.unne.edu.ar/handle/123456789/28014 |
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I48-R184-123456789-280142025-03-06T10:56:55Z Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes Asturias Arribas, Laura Delfino, Mario Raúl Alonso Lomillo, María Asunción Domínguez Renedo, Olga Nelfinavir Screen-printed electrode Electrochemical oxidation Carbon nanotubes This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC. 2021-06-01T21:35:23Z 2021-06-01T21:35:23Z 2016 Artículo Asturias Arribas, Laura, et.al., 2016. Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes. Electroanalysis. Weinheim: Wiley VCH Verlag, vol. 28, no. 9, p. 1-7. ISSN 1040-0397. 1040-0397 http://repositorio.unne.edu.ar/handle/123456789/28014 eng openAccess http://creativecommons.org/licenses/by-nc-nd/2.5/ar/ application/pdf application/pdf Wiley VCH Verlag Electroanalysis, 2016, vol. 28, no. 9, p. 1-7. |
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Universidad Nacional del Nordeste |
institution_str |
I-48 |
repository_str |
R-184 |
collection |
RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE) |
language |
Inglés |
topic |
Nelfinavir Screen-printed electrode Electrochemical oxidation Carbon nanotubes |
spellingShingle |
Nelfinavir Screen-printed electrode Electrochemical oxidation Carbon nanotubes Asturias Arribas, Laura Delfino, Mario Raúl Alonso Lomillo, María Asunción Domínguez Renedo, Olga Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
topic_facet |
Nelfinavir Screen-printed electrode Electrochemical oxidation Carbon nanotubes |
description |
This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC. |
format |
Artículo |
author |
Asturias Arribas, Laura Delfino, Mario Raúl Alonso Lomillo, María Asunción Domínguez Renedo, Olga |
author_facet |
Asturias Arribas, Laura Delfino, Mario Raúl Alonso Lomillo, María Asunción Domínguez Renedo, Olga |
author_sort |
Asturias Arribas, Laura |
title |
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
title_short |
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
title_full |
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
title_fullStr |
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
title_full_unstemmed |
Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
title_sort |
electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes |
publisher |
Wiley VCH Verlag |
publishDate |
2021 |
url |
http://repositorio.unne.edu.ar/handle/123456789/28014 |
work_keys_str_mv |
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_version_ |
1832343405160562688 |