Severe lymphoplasmacytic cholecystitis in a canine: a case report
Cholecystitis in dogs is a condition that often does not receive the same attention as diseases of the hepatic parenchyma. Two probable routes of infection have been identified: the ascending route from the duodenum through the common bile duct and/or the hematogenous route through the enterohepatic...
| Autores principales: | , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional del Nordeste
2024
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| Materias: | |
| Acceso en línea: | https://revistas.unne.edu.ar/index.php/vet/article/view/7861 |
| Aporte de: |
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I48-R154-article-7861 |
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Universidad Nacional del Nordeste |
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I-48 |
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R-154 |
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Revistas UNNE - Universidad Nacional del Noroeste (UNNE) |
| language |
Español |
| format |
Artículo revista |
| topic |
Gallbladder Cholecystectomy Domestic canines Vesícula biliar Colecistectomía Caninos domésticos |
| spellingShingle |
Gallbladder Cholecystectomy Domestic canines Vesícula biliar Colecistectomía Caninos domésticos Villanueva, Pablo M. Venegas, V.L. Angulo Lewylle, M. Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| topic_facet |
Gallbladder Cholecystectomy Domestic canines Vesícula biliar Colecistectomía Caninos domésticos |
| author |
Villanueva, Pablo M. Venegas, V.L. Angulo Lewylle, M. |
| author_facet |
Villanueva, Pablo M. Venegas, V.L. Angulo Lewylle, M. |
| author_sort |
Villanueva, Pablo M. |
| title |
Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| title_short |
Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| title_full |
Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| title_fullStr |
Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| title_full_unstemmed |
Severe lymphoplasmacytic cholecystitis in a canine: a case report |
| title_sort |
severe lymphoplasmacytic cholecystitis in a canine: a case report |
| description |
Cholecystitis in dogs is a condition that often does not receive the same attention as diseases of the hepatic parenchyma. Two probable routes of infection have been identified: the ascending route from the duodenum through the common bile duct and/or the hematogenous route through the enterohepatic circulation. This work describes a case of a 14-year-old female canine that presented an exacerbation of chronic cholecystitis, manifesting small intestine diarrhea and hyporexia of one month of progression. Empirical treatment was administered with ursodeoxycholic acid 15 mg kg-1 every 12 h, omeprazole 1 mg kg-1 every 12 h orally, and enrofloxacin 5 mg kg-1 every 24 h subcutaneously. This treatment initially resolved the clinical signs; however, the dog experienced a relapse. Cystocentesis of the gallbladder was performed and bile was cultured, obtaining a negative result. Due to the chronic changes observed in the gallbladder and cystic duct on ultrasound, it was elected to perform a cholecystectomy together with cystic duct ablation. Cytology of the gallbladder content showed purulent content, while the culture and antibiogram indicated the presence of Escherichia coli sensitive to cefovecin (8 mg kg-1 every 14 days, 2 doses). Surgical ablation was performed. Histopathology of the gallbladder and cystic duct revealed marked inflammation characterized by the presence of abundant lymphocytes, plasmacytes, and histiocytes. Due to inflammation in the remaining biliary tree, treatment with prednisolone was performed (initial dose of 1 mg kg-1 every 12 hours for 20 days, with gradual reduction of the dose by half at 20-day intervals until the treatment was completely discontinued, which resulted in the absence of digestive signs in the patient. |
| publisher |
Universidad Nacional del Nordeste |
| publishDate |
2024 |
| url |
https://revistas.unne.edu.ar/index.php/vet/article/view/7861 |
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AT villanuevapablom severelymphoplasmacyticcholecystitisinacanineacasereport AT venegasvl severelymphoplasmacyticcholecystitisinacanineacasereport AT angulolewyllem severelymphoplasmacyticcholecystitisinacanineacasereport AT villanuevapablom colecistitislinfoplasmociticaseveraenuncaninodescripciondeuncasoclinico AT venegasvl colecistitislinfoplasmociticaseveraenuncaninodescripciondeuncasoclinico AT angulolewyllem colecistitislinfoplasmociticaseveraenuncaninodescripciondeuncasoclinico |
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2025-05-17T05:10:31Z |
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2025-05-17T05:10:31Z |
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I48-R154-article-78612024-11-01T13:19:27Z Severe lymphoplasmacytic cholecystitis in a canine: a case report Colecistitis linfoplasmocítica severa en un canino: descripción de un caso clínico Villanueva, Pablo M. Venegas, V.L. Angulo Lewylle, M. Gallbladder Cholecystectomy Domestic canines Vesícula biliar Colecistectomía Caninos domésticos Cholecystitis in dogs is a condition that often does not receive the same attention as diseases of the hepatic parenchyma. Two probable routes of infection have been identified: the ascending route from the duodenum through the common bile duct and/or the hematogenous route through the enterohepatic circulation. This work describes a case of a 14-year-old female canine that presented an exacerbation of chronic cholecystitis, manifesting small intestine diarrhea and hyporexia of one month of progression. Empirical treatment was administered with ursodeoxycholic acid 15 mg kg-1 every 12 h, omeprazole 1 mg kg-1 every 12 h orally, and enrofloxacin 5 mg kg-1 every 24 h subcutaneously. This treatment initially resolved the clinical signs; however, the dog experienced a relapse. Cystocentesis of the gallbladder was performed and bile was cultured, obtaining a negative result. Due to the chronic changes observed in the gallbladder and cystic duct on ultrasound, it was elected to perform a cholecystectomy together with cystic duct ablation. Cytology of the gallbladder content showed purulent content, while the culture and antibiogram indicated the presence of Escherichia coli sensitive to cefovecin (8 mg kg-1 every 14 days, 2 doses). Surgical ablation was performed. Histopathology of the gallbladder and cystic duct revealed marked inflammation characterized by the presence of abundant lymphocytes, plasmacytes, and histiocytes. Due to inflammation in the remaining biliary tree, treatment with prednisolone was performed (initial dose of 1 mg kg-1 every 12 hours for 20 days, with gradual reduction of the dose by half at 20-day intervals until the treatment was completely discontinued, which resulted in the absence of digestive signs in the patient. La colecistitis en perros es una afección que a menudo no recibe la misma atención que a las enfermedades del parénquima hepático. Se han identificado dos rutas probables de infección: la vía ascendente desde el duodeno a través del conducto biliar común y/o la vía hematógena a través de la circulación enterohepática. Este trabajo describe un caso de una hembra canina de 14 años que presentó una agudización de una colecistitis crónica, manifestando diarrea de intestino delgado e hiporexia de un mes de progresión. Se administró un tratamiento empírico con ácido ursodesoxicólico 15 mg kg-1 cada 12 h, omeprazol 1 mg kg-1 cada 12 h por vía oral y enrofloxacina 5 mg kg-1 cada 24 h por vía subcutánea. Este tratamiento inicialmente resolvió los signos clínicos, sin embargo, la perra experimentó una recaída. Se realizó la cistocentesis de la vesícula biliar y se cultivó la bilis, obteniendo un resultado negativo. Debido a los cambios crónicos observados en la vesícula biliar y el conducto cístico en la ecografía, se optó por realizar una colecistectomía junto con la ablación del conducto cístico. La citología del contenido de la vesícula biliar mostró un contenido purulento, mientras que el cultivo y antibiograma indicaron la presencia de Escherichia coli sensible a cefovecina (8 mg kg-1 cada 14 días, 2 dosis). Se realizó la ablación quirúrgica. La histopatología de la vesícula biliar y el conducto cístico reveló una marcada inflamación caracterizada por la presencia de abundantes linfocitos, plasmocitos e histiocitos. Debido a la inflamación en el árbol biliar remanente, se realizó un tratamiento con prednisolona (dosis inicial de 1 mg kg-1 cada 12 horas durante 20 días, con reducción gradual de la dosis a la mitad en intervalos de 20 días hasta suspender completamente el tratamiento), lo cual resultó en la ausencia de signos digestivos en la paciente. Universidad Nacional del Nordeste 2024-11-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/7861 10.30972/vet.3527861 Revista Veterinaria; Vol. 35 Núm. 2 (2024); 37-42 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/7861/7383 https://creativecommons.org/licenses/by-nc/4.0 |