Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium

In the last decades, infections by several serovars of Salmonella have become relevant worldwide, not only due to their impact on veterinary health and animal production, but also because they may serve as a source of infection for the human population. Pigs can be infected by several Salmonella ser...

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Autores principales: Joaquim, Patricia, Balbiani, F., Delgado, F., Redondo, Leandro, Cappuccio, Javier, Chacana, Pablo
Formato: Artículo revista
Lenguaje:Inglés
Publicado: Universidad Nacional del Nordeste 2023
Materias:
Salmonella Typhimurium
Pigs
Experimental infection
Colonization
Enteric infection
Systemic infection
Bacteriological analysis
Serological analysis
Histopathological analysis
Cerdos
Infección experimental
Colonización
Infección entérica
Infección sistémica
Análisis bacteriológico
Análisis serológico
Análisis histopatológico
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/7048
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-7048
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institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Inglés
format Artículo revista
topic Salmonella Typhimurium
Pigs
Experimental infection
Colonization
Enteric infection
Systemic infection
Bacteriological analysis
Serological analysis
Histopathological analysis
Salmonella Typhimurium
Cerdos
Infección experimental
Colonización
Infección entérica
Infección sistémica
Análisis bacteriológico
Análisis serológico
Análisis histopatológico
spellingShingle Salmonella Typhimurium
Pigs
Experimental infection
Colonization
Enteric infection
Systemic infection
Bacteriological analysis
Serological analysis
Histopathological analysis
Salmonella Typhimurium
Cerdos
Infección experimental
Colonización
Infección entérica
Infección sistémica
Análisis bacteriológico
Análisis serológico
Análisis histopatológico
Joaquim, Patricia
Balbiani, F.
Delgado, F.
Redondo, Leandro
Cappuccio, Javier
Chacana, Pablo
Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
topic_facet Salmonella Typhimurium
Pigs
Experimental infection
Colonization
Enteric infection
Systemic infection
Bacteriological analysis
Serological analysis
Histopathological analysis
Salmonella Typhimurium
Cerdos
Infección experimental
Colonización
Infección entérica
Infección sistémica
Análisis bacteriológico
Análisis serológico
Análisis histopatológico
author Joaquim, Patricia
Balbiani, F.
Delgado, F.
Redondo, Leandro
Cappuccio, Javier
Chacana, Pablo
author_facet Joaquim, Patricia
Balbiani, F.
Delgado, F.
Redondo, Leandro
Cappuccio, Javier
Chacana, Pablo
author_sort Joaquim, Patricia
title Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
title_short Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
title_full Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
title_fullStr Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
title_full_unstemmed Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium
title_sort bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with salmonella typhimurium
description In the last decades, infections by several serovars of Salmonella have become relevant worldwide, not only due to their impact on veterinary health and animal production, but also because they may serve as a source of infection for the human population. Pigs can be infected by several Salmonella serovars, being S. Typhimurium one of the most frequently isolated worldwide. In this context, the evaluation of strategies to control Salmonella in farms demands the understanding of the pathogenesis of the microorganism. Thus, the objective of this work was to carry out an experimental infection in 50-day-old pigs using a field strain of S. Typhimurium to evaluate the excretion of the microorganism, organs colonization and the development of histological injuries over the 13-day trial period. Disease was successfully reproduced in eight animals, and two clinical patterns were identified. In four animals, a primarily enteric pattern was observed, where the infection was limited to the gastrointestinal tract, while in another four pigs, enteric and systemic infection with variable fecal excretion and invasion of internal organs was observed. These two infectious patterns were accompanied by changes in fecal consistency and reduced daily weight gain or weight loss in the animals. The observation of two different infectious patterns highlights the need to consider the complexity of the pathogenicity of Salmonella Typhimurium infection in pigs.
publisher Universidad Nacional del Nordeste
publishDate 2023
url https://revistas.unne.edu.ar/index.php/vet/article/view/7048
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last_indexed 2024-08-21T22:35:53Z
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spelling I48-R154-article-70482023-11-28T12:58:54Z Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium Estudio bacteriológico, serológico e histopatológico de lechones destetados infectados experimentalmente con Salmonella Typhimurium Joaquim, Patricia Balbiani, F. Delgado, F. Redondo, Leandro Cappuccio, Javier Chacana, Pablo Salmonella Typhimurium Pigs Experimental infection Colonization Enteric infection Systemic infection Bacteriological analysis Serological analysis Histopathological analysis Salmonella Typhimurium Cerdos Infección experimental Colonización Infección entérica Infección sistémica Análisis bacteriológico Análisis serológico Análisis histopatológico In the last decades, infections by several serovars of Salmonella have become relevant worldwide, not only due to their impact on veterinary health and animal production, but also because they may serve as a source of infection for the human population. Pigs can be infected by several Salmonella serovars, being S. Typhimurium one of the most frequently isolated worldwide. In this context, the evaluation of strategies to control Salmonella in farms demands the understanding of the pathogenesis of the microorganism. Thus, the objective of this work was to carry out an experimental infection in 50-day-old pigs using a field strain of S. Typhimurium to evaluate the excretion of the microorganism, organs colonization and the development of histological injuries over the 13-day trial period. Disease was successfully reproduced in eight animals, and two clinical patterns were identified. In four animals, a primarily enteric pattern was observed, where the infection was limited to the gastrointestinal tract, while in another four pigs, enteric and systemic infection with variable fecal excretion and invasion of internal organs was observed. These two infectious patterns were accompanied by changes in fecal consistency and reduced daily weight gain or weight loss in the animals. The observation of two different infectious patterns highlights the need to consider the complexity of the pathogenicity of Salmonella Typhimurium infection in pigs. En las últimas décadas las infecciones por diferentes serovariedades de Salmonella han adquirido importancia a nivel mundial, no solo por su impacto en la sanidad y en la producción de los animales, sino también porque estos constituyen una fuente de infección para los humanos. Los cerdos pueden estar infectados o ser portadores de distintas serovariedades con potencial zoonótico, siendo S. Typhimurium una de las más frecuentemente aisladas a nivel mundial. En este contexto, la evaluación de estrategias para el control de Salmonella en granjas exige el conocimiento de la patogenia del microorganismo. El objetivo de este trabajo fue realizar una infección experimental en cerdos de 50 días de edad utilizando una cepa de campo de S. Typhimurium para evaluar la excreción del microorganismo, la colonización de órganos y el desarrollo de lesiones histológicas durante los 13 días del ensayo. Se logró reproducir la enfermedad en ocho animales y se pudo identificar dos cuadros clínicos. En cuatro animales se observó un cuadro principalmente entérico, en el que la infección estuvo limitada al tracto gastrointestinal; mientras que en otros cuatro cerdos se observó infección entérica y sistémica con excreción fecal variable e invasión de órganos internos. Estos dos cuadros infecciosos estuvieron acompañados de cambios en la consistencia de la materia fecal y menor ganancia diaria de peso o adelgazamiento de los animales. La observación de dos cuadros infecciosos diferentes muestra la necesidad de considerar la complejidad de la patogenicidad de la infección por Salmonella Typhimurium en cerdos. Universidad Nacional del Nordeste 2023-11-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/7048 10.30972/vet.3427048 Revista Veterinaria; Vol. 34 Núm. 2 (2023); 81-90 1669-6840 1668-4834 eng https://revistas.unne.edu.ar/index.php/vet/article/view/7048/6504 https://creativecommons.org/licenses/by/2.5/ar/

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