Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina

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Tests of neutralization of hemorrhagic and edema–forming activities from the venom of Bothrops alternatus (víbora de la cruz) one month–old offsprings were performed using a bivalent antivenom, produced by Laboratorio Central de Salud Pública in La Plata, Buenos Aires, Argentina. We determined that...

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Autores principales: Zeinsteger, P. A., Maruñak, S. L., Acosta de Pérez, O.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2016
Materias:
Bothrops alternatus
neutralization
hemorrhagic activity
edema–forming activity.
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/665
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-665
record_format ojs
spelling I48-R154-article-6652025-02-12T21:57:04Z Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina Zeinsteger, P. A. Maruñak, S. L. Acosta de Pérez, O. Bothrops alternatus neutralization hemorrhagic activity edema–forming activity. Tests of neutralization of hemorrhagic and edema–forming activities from the venom of Bothrops alternatus (víbora de la cruz) one month–old offsprings were performed using a bivalent antivenom, produced by Laboratorio Central de Salud Pública in La Plata, Buenos Aires, Argentina. We determined that 172 µl of the antivenom neutralize 50 % of the hemorrhagic activity, induced by 9 µg of the venom (challenge dose). Neutralization of edema–forming activity was more effective when the antivenom was administered previous to the venom. We conclude that the antivenom neutralizes the studied toxic activities, taking into account that for its production horses are immunized using venom from adult snakes. Universidad Nacional del Nordeste 2016-10-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/665 10.30972/vet.101 y 2665 Revista Veterinaria; Vol. 10-11, Núm. 1-2 (1999-2000); 22-24 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/665/573 Derechos de autor 1999 P. A. Zeinsteger, S. L. Maruñak, O. Acosta de Pérez https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic Bothrops alternatus
neutralization
hemorrhagic activity
edema–forming activity.
spellingShingle Bothrops alternatus
neutralization
hemorrhagic activity
edema–forming activity.
Zeinsteger, P. A.
Maruñak, S. L.
Acosta de Pérez, O.
Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
topic_facet Bothrops alternatus
neutralization
hemorrhagic activity
edema–forming activity.
author Zeinsteger, P. A.
Maruñak, S. L.
Acosta de Pérez, O.
author_facet Zeinsteger, P. A.
Maruñak, S. L.
Acosta de Pérez, O.
author_sort Zeinsteger, P. A.
title Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
title_short Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
title_full Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
title_fullStr Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
title_full_unstemmed Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina
title_sort neutralization of the hemorrhagic and edema–forming activities from venom of bothrops alternatus offsprings from argentina
description Tests of neutralization of hemorrhagic and edema–forming activities from the venom of Bothrops alternatus (víbora de la cruz) one month–old offsprings were performed using a bivalent antivenom, produced by Laboratorio Central de Salud Pública in La Plata, Buenos Aires, Argentina. We determined that 172 µl of the antivenom neutralize 50 % of the hemorrhagic activity, induced by 9 µg of the venom (challenge dose). Neutralization of edema–forming activity was more effective when the antivenom was administered previous to the venom. We conclude that the antivenom neutralizes the studied toxic activities, taking into account that for its production horses are immunized using venom from adult snakes.
publisher Universidad Nacional del Nordeste
publishDate 2016
url https://revistas.unne.edu.ar/index.php/vet/article/view/665
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AT marunaksl neutralizationofthehemorrhagicandedemaformingactivitiesfromvenomofbothropsalternatusoffspringsfromargentina
AT acostadeperezo neutralizationofthehemorrhagicandedemaformingactivitiesfromvenomofbothropsalternatusoffspringsfromargentina
first_indexed 2025-05-17T05:07:37Z
last_indexed 2025-05-17T05:07:37Z
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