Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs

Techniques such as endoscopic mucosal resection and endoscopic submucosal dissection, are minimally invasive therapeutic techniques widely spread in human medicine, but unknown in veterinary medicine. This preliminary study compared 4 gastric submucosal injection solutions: hyaluronic acid, 10% glyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Orellana, M. C., Ayala, I.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2021
Materias:
cerdos
endoscopía
resección mucosa
disección submucosa
tiempo de permanencia
pigs
endoscopy
mucosal resection
submucosal dissection
time of permanency
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/4742
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-4742
record_format ojs
spelling I48-R154-article-47422025-02-12T21:59:25Z Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs Soluciones de elevación y su potencial aplicación en resección mucosa y disección submucosa endoscópica en cerdos Orellana, M. C. Ayala, I. cerdos endoscopía resección mucosa disección submucosa tiempo de permanencia pigs endoscopy mucosal resection submucosal dissection time of permanency Techniques such as endoscopic mucosal resection and endoscopic submucosal dissection, are minimally invasive therapeutic techniques widely spread in human medicine, but unknown in veterinary medicine. This preliminary study compared 4 gastric submucosal injection solutions: hyaluronic acid, 10% glycerol, 6% starch and 0.9% physiological saline. By injecting 5 ml of each solution into ex vivo stomachs of pigs and subsequently assessing the elevation profile of each substance and comparing groups by means of the Student’s t-test with p<0.05. The initial diameter of the mucosal elevation showed no differences between groups and was around 4 cm. The maximum height was obtained by hyaluronic acid (10.3 mm). Finally, hyaluronic acid showed a longer permanence time (68 minutes). These preliminary results are promising because they allow the first approach of veterinary doctors to these techniques. Técnicas como la resección mucosa endoscópica y la disección submucosa endoscópica son prácticas terapéuticas mínimamente invasivas, ampliamente difundidas en medicina humana, pero desconocidas en medicina veterinaria. Este estudio preliminar comparó 4 soluciones de inyección submucosa a nivel gástrico: ácido hialurónico, glicerol al 10%, almidón al 6% y solución salina fisiológica al 0,9%. Inyectando 5 ml de cada solución en estómagos ex vivo de cerdo y posteriormente valorando el perfil de elevación de cada sustancia, se compararon los grupos por medio de la prueba t de Student con p<0,05. El diámetro inicial de la elevación de mucosa no mostró diferencias entre grupos y estuvieron en torno a los 4 cm. La altura máxima fue obtenida por el ácido hialurónico (10,3 mm). Finalmente, el ácido hialurónico mostró el mayor tiempo de permanencia (68 minutos). Estos resultados preliminares, son prometedores por cuanto permiten el primer acercamiento de médicos veterinarios a estas técnicas. Universidad Nacional del Nordeste 2021-04-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/4742 10.30972/vet.3124742 Revista Veterinaria; Vol. 31 Núm. 2 (2020); 183-185 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/4742/4441 Derechos de autor 2021 M. C. Orellana, I. Ayala https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic cerdos
endoscopía
resección mucosa
disección submucosa
tiempo de permanencia
pigs
endoscopy
mucosal resection
submucosal dissection
time of permanency
spellingShingle cerdos
endoscopía
resección mucosa
disección submucosa
tiempo de permanencia
pigs
endoscopy
mucosal resection
submucosal dissection
time of permanency
Orellana, M. C.
Ayala, I.
Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
topic_facet cerdos
endoscopía
resección mucosa
disección submucosa
tiempo de permanencia
pigs
endoscopy
mucosal resection
submucosal dissection
time of permanency
author Orellana, M. C.
Ayala, I.
author_facet Orellana, M. C.
Ayala, I.
author_sort Orellana, M. C.
title Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
title_short Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
title_full Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
title_fullStr Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
title_full_unstemmed Lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
title_sort lifting solutions and their potential application in mucosal resection and endoscopic submucosal dissection in pigs
description Techniques such as endoscopic mucosal resection and endoscopic submucosal dissection, are minimally invasive therapeutic techniques widely spread in human medicine, but unknown in veterinary medicine. This preliminary study compared 4 gastric submucosal injection solutions: hyaluronic acid, 10% glycerol, 6% starch and 0.9% physiological saline. By injecting 5 ml of each solution into ex vivo stomachs of pigs and subsequently assessing the elevation profile of each substance and comparing groups by means of the Student’s t-test with p<0.05. The initial diameter of the mucosal elevation showed no differences between groups and was around 4 cm. The maximum height was obtained by hyaluronic acid (10.3 mm). Finally, hyaluronic acid showed a longer permanence time (68 minutes). These preliminary results are promising because they allow the first approach of veterinary doctors to these techniques.
publisher Universidad Nacional del Nordeste
publishDate 2021
url https://revistas.unne.edu.ar/index.php/vet/article/view/4742
work_keys_str_mv AT orellanamc liftingsolutionsandtheirpotentialapplicationinmucosalresectionandendoscopicsubmucosaldissectioninpigs
AT ayalai liftingsolutionsandtheirpotentialapplicationinmucosalresectionandendoscopicsubmucosaldissectioninpigs
AT orellanamc solucionesdeelevacionysupotencialaplicacionenreseccionmucosaydiseccionsubmucosaendoscopicaencerdos
AT ayalai solucionesdeelevacionysupotencialaplicacionenreseccionmucosaydiseccionsubmucosaendoscopicaencerdos
first_indexed 2025-05-17T05:10:15Z
last_indexed 2025-05-17T05:10:15Z
_version_ 1832343165427777536

Ejemplares similares