Chagas' disease reactivation with skin symptoms in a patient with kidney transplant

Immunodepressed patients in the intermediate phase of Chagas' disease may undergo reactivation of the disease together with atypical symptoms. The case of an immunodepressed kidney transplant patient with reactivation of Chagas' disease with skin symptoms is reported. A 65-year-old man pre...

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Detalles Bibliográficos
Autores principales: Gallerano, Verónica, Consigli, Javier Enrique, Pereyra, Susana, Gómez Zanni, Susana, Danielo, Cristian, Gallerano, Rafael H., Guidi, Andrés Emilio
Formato: Artículo
Lenguaje:Español
Publicado: 2007
Materias:
R Medicina (General)
RL Dermatología
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4027/1/A_Gallerano_Consigli_Pereyra_Zanni_Danielo_Gallerano_Guidi.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4027
record_format dspace
spelling I38-R144-40272025-04-10T19:03:36Z http://pa.bibdigital.ucc.edu.ar/4027/ Chagas' disease reactivation with skin symptoms in a patient with kidney transplant Gallerano, Verónica Consigli, Javier Enrique Pereyra, Susana Gómez Zanni, Susana Danielo, Cristian Gallerano, Rafael H. Guidi, Andrés Emilio R Medicina (General) RL Dermatología Immunodepressed patients in the intermediate phase of Chagas' disease may undergo reactivation of the disease together with atypical symptoms. The case of an immunodepressed kidney transplant patient with reactivation of Chagas' disease with skin symptoms is reported. A 65-year-old man presented with infiltrated erythematous lesions on the anterior aspect of the right thigh of 2 weeks' duration. The lesions later extended to the abdomen, thorax, and lower limbs. In the histologic skin examination, amastigotes and Trypanosoma cruzi trypoamastigotes were observed. A fresh smear showed positive parasitemia. Using the Strout hemoconcentration method, multiple Trypanosoma cruzi trypoamastigotes with motility could be seen. Polymerase chain reaction was positive for Trypanosoma cruzi. An immunofluorescence test was positive (1:64) and there was hemoagglutination (1:32). Treatment was started with benznidazole, 7mg/kg/day. The patient did not evolve favorably and died 20 days after hospitalization. Skin lesions may be a manifestation of the reactivation of Chagas' disease in immunosuppressed patients. All patients with positive Chagas serology who require immunosuppressant drugs should receive specific treatment for Chagas' disease. 2007-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4027/1/A_Gallerano_Consigli_Pereyra_Zanni_Danielo_Gallerano_Guidi.pdf Gallerano, Verónica, Consigli, Javier Enrique, Pereyra, Susana, Gómez Zanni, Susana, Danielo, Cristian, Gallerano, Rafael H. and Guidi, Andrés Emilio (2007) Chagas' disease reactivation with skin symptoms in a patient with kidney transplant. International Journal of Dermatology, 46 (6). pp. 607-610. ISSN 1365-4632 info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-4632.2007.03127.x
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic R Medicina (General)
RL Dermatología
spellingShingle R Medicina (General)
RL Dermatología
Gallerano, Verónica
Consigli, Javier Enrique
Pereyra, Susana
Gómez Zanni, Susana
Danielo, Cristian
Gallerano, Rafael H.
Guidi, Andrés Emilio
Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
topic_facet R Medicina (General)
RL Dermatología
description Immunodepressed patients in the intermediate phase of Chagas' disease may undergo reactivation of the disease together with atypical symptoms. The case of an immunodepressed kidney transplant patient with reactivation of Chagas' disease with skin symptoms is reported. A 65-year-old man presented with infiltrated erythematous lesions on the anterior aspect of the right thigh of 2 weeks' duration. The lesions later extended to the abdomen, thorax, and lower limbs. In the histologic skin examination, amastigotes and Trypanosoma cruzi trypoamastigotes were observed. A fresh smear showed positive parasitemia. Using the Strout hemoconcentration method, multiple Trypanosoma cruzi trypoamastigotes with motility could be seen. Polymerase chain reaction was positive for Trypanosoma cruzi. An immunofluorescence test was positive (1:64) and there was hemoagglutination (1:32). Treatment was started with benznidazole, 7mg/kg/day. The patient did not evolve favorably and died 20 days after hospitalization. Skin lesions may be a manifestation of the reactivation of Chagas' disease in immunosuppressed patients. All patients with positive Chagas serology who require immunosuppressant drugs should receive specific treatment for Chagas' disease.
format Artículo
author Gallerano, Verónica
Consigli, Javier Enrique
Pereyra, Susana
Gómez Zanni, Susana
Danielo, Cristian
Gallerano, Rafael H.
Guidi, Andrés Emilio
author_facet Gallerano, Verónica
Consigli, Javier Enrique
Pereyra, Susana
Gómez Zanni, Susana
Danielo, Cristian
Gallerano, Rafael H.
Guidi, Andrés Emilio
author_sort Gallerano, Verónica
title Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
title_short Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
title_full Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
title_fullStr Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
title_full_unstemmed Chagas' disease reactivation with skin symptoms in a patient with kidney transplant
title_sort chagas' disease reactivation with skin symptoms in a patient with kidney transplant
publishDate 2007
url http://pa.bibdigital.ucc.edu.ar/4027/1/A_Gallerano_Consigli_Pereyra_Zanni_Danielo_Gallerano_Guidi.pdf
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