Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors

Despite the great benefits of chemotherapy, the ability of tumor cells to acquire crossresistance to multiple antineoplastic drugs (MDR) results in a drastic reduction in the efficacy of these agents. Of greatest concern is the consequent failure in clinical practice, which remains one of the major...

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Autores principales: Rijo, Patricia, Athanassopoulos, Constantinos M., Carpinella, María Cecilia
Formato: Artículo acceptedVersion
Lenguaje:Español
Publicado: 2022
Materias:
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3650/1/A_Rijo_Athanassopoulos_Carpinella.pdf
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id I38-R144-3650
record_format dspace
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic QD Química
spellingShingle QD Química
Rijo, Patricia
Athanassopoulos, Constantinos M.
Carpinella, María Cecilia
Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
topic_facet QD Química
description Despite the great benefits of chemotherapy, the ability of tumor cells to acquire crossresistance to multiple antineoplastic drugs (MDR) results in a drastic reduction in the efficacy of these agents. Of greatest concern is the consequent failure in clinical practice, which remains one of the major barriers to successful cancer treatment. To improve patient outcome, novel efficacious anti-cancer agents or approaches to reverse MDR are necessary. Plants have been an endless and vital source of pharmacologically active compounds, many of which are widely used in cancer therapies, not only to control tumor cells, but also to increase their sensitivity to chemotherapeutic agents. The structural diversity and array of biological properties of plant-derived metabolites, in particular against tumors, make these strong candidates to combat MDR cells or establish their scaffolds as a valuable base for the synthesis of derivatives. This enormous potential of plants to tackle MDR tumors encouraged us to publish this Research Topic to display and discuss the cutting-edge research in the field. As editors, it was a pleasure to review a wide range of fascinating articles with different perspectives, and we summarize here the main findings of accepted articles.
format Artículo
Artículo
acceptedVersion
author Rijo, Patricia
Athanassopoulos, Constantinos M.
Carpinella, María Cecilia
author_facet Rijo, Patricia
Athanassopoulos, Constantinos M.
Carpinella, María Cecilia
author_sort Rijo, Patricia
title Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
title_short Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
title_full Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
title_fullStr Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
title_full_unstemmed Editorial: Considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (MDR) tumors
title_sort editorial: considering plant metabolites and their synthetic derivatives as candidates for the development of drugs against multidrug resistant (mdr) tumors
publishDate 2022
url http://pa.bibdigital.ucc.edu.ar/3650/1/A_Rijo_Athanassopoulos_Carpinella.pdf
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