Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina

The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian can...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bella, Santiago Rafael, Llugdar, José Roberto, Biagi Bistoni, Marta Inés, Pellicioni, Patricia, Lerda, Daniel Enrique, Labrador, Jorge, Fernández Cruz, G., Martins, C.
Formato: Artículo acceptedVersion
Lenguaje:Inglés
Publicado: Academicians' Research Center 2015
Materias:
R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/1466/1/A_Lerda_Bella_Llugdar.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-1466
record_format dspace
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Inglés
orig_language_str_mv eng
topic R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
spellingShingle R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
Bella, Santiago Rafael
Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
topic_facet R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
description The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.
format Artículo
Artículo
acceptedVersion
author Bella, Santiago Rafael
Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
author_facet Bella, Santiago Rafael
Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
author_sort Bella, Santiago Rafael
title Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_short Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_full Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_fullStr Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_full_unstemmed Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_sort frequency of mutations in brca1 and brca2 genes in women with breast cancer in córdoba, argentina
publisher Academicians' Research Center
publishDate 2015
url http://pa.bibdigital.ucc.edu.ar/1466/1/A_Lerda_Bella_Llugdar.pdf
work_keys_str_mv AT bellasantiagorafael frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT llugdarjoseroberto frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT biagibistonimartaines frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT pellicionipatricia frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT lerdadanielenrique frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT labradorjorge frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT fernandezcruzg frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
AT martinsc frequencyofmutationsinbrca1andbrca2genesinwomenwithbreastcancerincordobaargentina
bdutipo_str Repositorios
_version_ 1764820534813523969

Ejemplares similares