Mhc-B haplotypes in "Campero-Inta" chicken synthetic line

Abstract: The major histocompatibility complex-B (MHC-B) in chickens is a cluster of genes located on chromosome 16. The chicken MHC-B is known to be highly associated with resistance to numerous diseases caused by viruses, bacteria, and parasitic pathogens. Since the level of resistance varies with...

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Autores principales: Iglesias, Gabriela M., Canet, Zulma E., Cantaro, Horacio, Miquel, María C., Melo, Julián E., Miller, Marcia M., Berres, Mark E., Fulton, Janet E.
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2020
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/9666
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id I33-R139123456789-9666
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic COMPLEJO MAYOR DE HISTOCOMPATIBILIDAD
POLLOS
REPROUDCCION ANIMAL
HIBRIDACION
HAPLOTIPOS
INDUSTRIA ALIMENTARIA
spellingShingle COMPLEJO MAYOR DE HISTOCOMPATIBILIDAD
POLLOS
REPROUDCCION ANIMAL
HIBRIDACION
HAPLOTIPOS
INDUSTRIA ALIMENTARIA
Iglesias, Gabriela M.
Canet, Zulma E.
Cantaro, Horacio
Miquel, María C.
Melo, Julián E.
Miller, Marcia M.
Berres, Mark E.
Fulton, Janet E.
Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
topic_facet COMPLEJO MAYOR DE HISTOCOMPATIBILIDAD
POLLOS
REPROUDCCION ANIMAL
HIBRIDACION
HAPLOTIPOS
INDUSTRIA ALIMENTARIA
description Abstract: The major histocompatibility complex-B (MHC-B) in chickens is a cluster of genes located on chromosome 16. The chicken MHC-B is known to be highly associated with resistance to numerous diseases caused by viruses, bacteria, and parasitic pathogens. Since the level of resistance varies with MHC-B haplotypes, identification and classification of different haplotypes within lines is important for sustaining lines. The "Campero-INTA" chicken breed is a meat-type free-range poultry breed that was developed specifically for small producers in Argentina. Campero-INTA was started by selection in populations produced by crosses between a variety of established lines. MHC-B variation was examined in 65 samples obtained in 2002 using the VNTR marker LEI0258, a marker for MHC-B region. These samples plus and an additional 55 samples from 2018 were examined for variation using the MHC-B specific SNP panel that encompasses ∼230,000 bp of the MHC-B region. Eleven MHC-B SNP haplotypes with 6 LEI0258 alleles were identified in the 120 samples representing the Campero-INTA AH (male) line. Seven haplotypes originate from the breeds originally used in the development of Campero-INTA AH line. Two appear to be recombinant haplotypes. The origin of the remaining 2 is not known, but may be associated with genes introduced from crosses with the Fayoumi breed conducted more recently to sustain the line.
format Artículo
author Iglesias, Gabriela M.
Canet, Zulma E.
Cantaro, Horacio
Miquel, María C.
Melo, Julián E.
Miller, Marcia M.
Berres, Mark E.
Fulton, Janet E.
author_facet Iglesias, Gabriela M.
Canet, Zulma E.
Cantaro, Horacio
Miquel, María C.
Melo, Julián E.
Miller, Marcia M.
Berres, Mark E.
Fulton, Janet E.
author_sort Iglesias, Gabriela M.
title Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
title_short Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
title_full Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
title_fullStr Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
title_full_unstemmed Mhc-B haplotypes in "Campero-Inta" chicken synthetic line
title_sort mhc-b haplotypes in "campero-inta" chicken synthetic line
publisher Elsevier
publishDate 2020
url https://repositorio.uca.edu.ar/handle/123456789/9666
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