Does erythropoietin regulate TRPC channels in red blood cells?

Abstract: Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels). The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated...

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Autores principales: Danielczok, Jens, Hertz, Laura, Ruppenthal, Sandra, Kaiser, Elisabeth, Petkova-Kirova, Polina, Bogdanova, Anna, Krause, Elmar, Lipp, Peter, Freichel, Marc, Kaestner, Lars, Birnbaumer, Lutz
Formato: Artículo
Lenguaje:Inglés
Publicado: Karger Publishers 2019
Materias:
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8729
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id I33-R139123456789-8729
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
spellingShingle GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
Danielczok, Jens
Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
Does erythropoietin regulate TRPC channels in red blood cells?
topic_facet GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
description Abstract: Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels). The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated with an increase in intracellular Ca2+ upon stimulation with Erythropoietin (Epo). In contrast two independent studies on Epo-treated patients revealed diminished basal Ca2+ concentration or reduced phosphatidylserine exposure to the outer membrane leaflet.
format Artículo
author Danielczok, Jens
Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
author_facet Danielczok, Jens
Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
author_sort Danielczok, Jens
title Does erythropoietin regulate TRPC channels in red blood cells?
title_short Does erythropoietin regulate TRPC channels in red blood cells?
title_full Does erythropoietin regulate TRPC channels in red blood cells?
title_fullStr Does erythropoietin regulate TRPC channels in red blood cells?
title_full_unstemmed Does erythropoietin regulate TRPC channels in red blood cells?
title_sort does erythropoietin regulate trpc channels in red blood cells?
publisher Karger Publishers
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/8729
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