Histamine : a potential cytoprotective agent to improve cancer therapy?

Chemotherapy along with radiotherapy is a major treatment of medical oncology. Despite their therapeutic effects achieving local tumor control and in many cases controlling metastasis, both approaches can produce serious adverse effects to normal tissues either immediately or during the long term af...

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Autores principales: Martinel Lamas, Diego J., Nicoud, Melisa Beatriz, Sterle, Helena Andrea, Cremaschi, Graciela A., Medina, Vanina Araceli
Formato: Artículo
Lenguaje:Inglés
Publicado: Nature Research 2019
Materias:
MEDICINA
ONCOLOGIA
CANCER
TRATAMIENTO MEDICO
HISTAMINA
QUIMIOTERAPIA
RADIOTERAPIA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8700
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-8700
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic MEDICINA
ONCOLOGIA
CANCER
TRATAMIENTO MEDICO
HISTAMINA
QUIMIOTERAPIA
RADIOTERAPIA
spellingShingle MEDICINA
ONCOLOGIA
CANCER
TRATAMIENTO MEDICO
HISTAMINA
QUIMIOTERAPIA
RADIOTERAPIA
Martinel Lamas, Diego J.
Nicoud, Melisa Beatriz
Sterle, Helena Andrea
Cremaschi, Graciela A.
Medina, Vanina Araceli
Histamine : a potential cytoprotective agent to improve cancer therapy?
topic_facet MEDICINA
ONCOLOGIA
CANCER
TRATAMIENTO MEDICO
HISTAMINA
QUIMIOTERAPIA
RADIOTERAPIA
description Chemotherapy along with radiotherapy is a major treatment of medical oncology. Despite their therapeutic effects achieving local tumor control and in many cases controlling metastasis, both approaches can produce serious adverse effects to normal tissues either immediately or during the long term after treatment. Thus, their related toxicity frequently outweigh clinical benefits and worsen patient’s quality of life Regardless of the high incidence of cancer therapyassociated adverse reactions (e.g., hepato, hemato and cardio toxicities) and their significant impact on morbidity, mortality and health economics; as far as we know, there are no standard, clinically approved, effective agents that could improve the therapeutic index of chemo and radiotherapy, controlling these devastating side effects in patients undergoing anti-tumoral treatments. Therefore, the development of pharmacological approaches to effectively prevent conventional cancer therapy-induced toxicity is of utmost importance.
format Artículo
author Martinel Lamas, Diego J.
Nicoud, Melisa Beatriz
Sterle, Helena Andrea
Cremaschi, Graciela A.
Medina, Vanina Araceli
author_facet Martinel Lamas, Diego J.
Nicoud, Melisa Beatriz
Sterle, Helena Andrea
Cremaschi, Graciela A.
Medina, Vanina Araceli
author_sort Martinel Lamas, Diego J.
title Histamine : a potential cytoprotective agent to improve cancer therapy?
title_short Histamine : a potential cytoprotective agent to improve cancer therapy?
title_full Histamine : a potential cytoprotective agent to improve cancer therapy?
title_fullStr Histamine : a potential cytoprotective agent to improve cancer therapy?
title_full_unstemmed Histamine : a potential cytoprotective agent to improve cancer therapy?
title_sort histamine : a potential cytoprotective agent to improve cancer therapy?
publisher Nature Research
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/8700
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AT sterlehelenaandrea histamineapotentialcytoprotectiveagenttoimprovecancertherapy
AT cremaschigracielaa histamineapotentialcytoprotectiveagenttoimprovecancertherapy
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bdutipo_str Repositorios
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