Cognitive profiles of patients with early detected and treated congenital hypothyroidism

Mostrar todas las versiones(2)

Abstract: Introduction: Children with congenital hypothyroidism (CH) detected by newborn screening and adequately treated may have mild cognitive deficits. Objectives: To assess the intelligence quotient of children with CH and identify the presence of specific cognitive deficits. Population and met...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pardo Campos, María L., Musso, Mariel Fernanda, Keselman, Ana, Gruñeiro, Laura, Bergadá, Ignacio, Chiesa, Ana
Formato:	Artículo
Lenguaje:	Inglés
Publicado:	Sociedad Argentina de Pediatría 2019
Materias:	HIPOTIROIDISMO CONGENITO COGNICION FUNCION COGNITIVA PACIENTES PSICOPEDAGOGÍA
Acceso en línea:	https://repositorio.uca.edu.ar/handle/123456789/6208
Aporte de:	Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina

id	I33-R139123456789-6208
record_format	dspace
institution	Universidad Católica Argentina
institution_str	I-33
repository_str	R-139
collection	Repositorio Institucional de la Universidad Católica Argentina (UCA)
language	Inglés
topic	HIPOTIROIDISMO CONGENITO COGNICION FUNCION COGNITIVA PACIENTES PSICOPEDAGOGÍA
spellingShingle	HIPOTIROIDISMO CONGENITO COGNICION FUNCION COGNITIVA PACIENTES PSICOPEDAGOGÍA Pardo Campos, María L. Musso, Mariel Fernanda Keselman, Ana Gruñeiro, Laura Bergadá, Ignacio Chiesa, Ana Cognitive profiles of patients with early detected and treated congenital hypothyroidism
topic_facet	HIPOTIROIDISMO CONGENITO COGNICION FUNCION COGNITIVA PACIENTES PSICOPEDAGOGÍA
description	Abstract: Introduction: Children with congenital hypothyroidism (CH) detected by newborn screening and adequately treated may have mild cognitive deficits. Objectives: To assess the intelligence quotient of children with CH and identify the presence of specific cognitive deficits. Population and methods: A group of 60 children with CH detected by newborn screening, who were aged 9-10 years old and received adequate treatment since their first month of life was selected and compared to a control group of 60 children without CH in the same age range. Inclusion criteria: children without concurrent diseases, who were attending school in a single shift, and whose parents had at least completed secondary education. The following tests were administered during individual interviews: the Wechsler Intelligence Scale for Children (third edition), the Rey complex figure test, the Woodcock-Muñoz revised test, the Conners Continuous Performance Test II, the Illinois Test of Psycholinguistic Abilities, the verbal fluency test, the Knox Cube Test, the Trail Making Test, the faces test, and the 5 digit test. The statistical analysis was done using Student’s t tests (for independent samples) with Bonferroni’s correction (p < 0.002). Results. Even within the normal average range, significant differences were observed between both groups in terms of total intelligence quotient and performance intelligence quotient (small and moderate effect sizes, respectively). In terms of performance, children with hypothyroidism had a significantly poorer performance in processing speed, reaction times, attention, cognitive flexibility, visuoconstruction, and long-term memory. No significant differences were found between both groups in the verbal area. Conclusions. Children with congenital hypothyroidism and without mental disability had mild cognitive deficits, which should be taken into account for a comprehensive patient care. Key words: congenital hypothyroidism, cognitive functions, screening, mild cognitive deficit
format	Artículo
author	Pardo Campos, María L. Musso, Mariel Fernanda Keselman, Ana Gruñeiro, Laura Bergadá, Ignacio Chiesa, Ana
author_facet	Pardo Campos, María L. Musso, Mariel Fernanda Keselman, Ana Gruñeiro, Laura Bergadá, Ignacio Chiesa, Ana
author_sort	Pardo Campos, María L.
title	Cognitive profiles of patients with early detected and treated congenital hypothyroidism
title_short	Cognitive profiles of patients with early detected and treated congenital hypothyroidism
title_full	Cognitive profiles of patients with early detected and treated congenital hypothyroidism
title_fullStr	Cognitive profiles of patients with early detected and treated congenital hypothyroidism
title_full_unstemmed	Cognitive profiles of patients with early detected and treated congenital hypothyroidism
title_sort	cognitive profiles of patients with early detected and treated congenital hypothyroidism
publisher	Sociedad Argentina de Pediatría
publishDate	2019
url	https://repositorio.uca.edu.ar/handle/123456789/6208
work_keys_str_mv	AT pardocamposmarial cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism AT mussomarielfernanda cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism AT keselmanana cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism AT gruneirolaura cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism AT bergadaignacio cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism AT chiesaana cognitiveprofilesofpatientswithearlydetectedandtreatedcongenitalhypothyroidism
bdutipo_str	Repositorios
_version_	1764820528631119872

Cognitive profiles of patients with early detected and treated congenital hypothyroidism

Ejemplares similares