Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited

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Abstract: pomorphine is the oldest dopaminergic agent and was initially known for its emetic properties. Although Weill suggested using it to treat Parkinson’s disease (PD) in 1884, evidence about its antiparkinsonian efficacy was provided initially by Schwab and colleagues in 1951 and then by Cotzi...

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Autor principal: Pérez Lloret, Santiago
Formato: Artículo
Lenguaje:Inglés
Inglés
Publicado: 2019
Materias:
APOMORFINA
TRATAMIENTO
ENFERMEDAD DE PARKINSON
ENFERMEDADES NEUROGENERATIVAS
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/1635
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-1635
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
Inglés
topic APOMORFINA
TRATAMIENTO
ENFERMEDAD DE PARKINSON
ENFERMEDADES NEUROGENERATIVAS
spellingShingle APOMORFINA
TRATAMIENTO
ENFERMEDAD DE PARKINSON
ENFERMEDADES NEUROGENERATIVAS
Pérez Lloret, Santiago
Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
topic_facet APOMORFINA
TRATAMIENTO
ENFERMEDAD DE PARKINSON
ENFERMEDADES NEUROGENERATIVAS
description Abstract: pomorphine is the oldest dopaminergic agent and was initially known for its emetic properties. Although Weill suggested using it to treat Parkinson’s disease (PD) in 1884, evidence about its antiparkinsonian efficacy was provided initially by Schwab and colleagues in 1951 and then by Cotzias and co-workers in 1970. Subcutaneous injection of the drug displayed potent but short-live antiparkinsonian effects usually at the expense of vomiting and postural hypotension. These limitations coupled with the advent of orally-active dopamine receptor agonists led to a waning in the interest in the drug...
format Artículo
author Pérez Lloret, Santiago
author_facet Pérez Lloret, Santiago
author_sort Pérez Lloret, Santiago
title Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
title_short Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
title_full Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
title_fullStr Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
title_full_unstemmed Apomorphine for the treatment of refractory motor fluctuations in late stage Parkinson's disease : an old drug revisited
title_sort apomorphine for the treatment of refractory motor fluctuations in late stage parkinson's disease : an old drug revisited
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/1635
work_keys_str_mv AT perezlloretsantiago apomorphineforthetreatmentofrefractorymotorfluctuationsinlatestageparkinsonsdiseaseanolddrugrevisited
bdutipo_str Repositorios
_version_ 1764820525760118785

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