The chloride anion acts as a second messenger in mammalian cells modifying the expression of specific genes

Abstract: Background/Aims: Cystic Fibrosis (CF) is caused by mutations in the CFTR gene, encoding a cAMP-activated chloride (Cl-) channel. We have previously demonstrated that the expression of several genes can be modulated by the CFTR activity; among them, SRC, MTND4, CISD1, and IL1B. However, the...

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Autores principales: Valdivieso, Ángel Gabriel, Clauzure, Mariángeles, Massip Copiz, María Macarena, Santa Coloma, Tomás Antonio
Formato: Artículo
Lenguaje:Inglés
Inglés
Publicado: Karger International 2019
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/1454
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