Nosology and phenomenology of psychosis in movement disorders

Background: Psychotic symptoms, such as delusions and hallucinations, are part of the clinical picture of several conditions presenting movement disorders. Phenomenology and epidemiology of psychosis in Parkinson's disease have received wide attention; however, the presence of psychosis in othe...

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Autores principales: Rossi, Malco Damián, Farcy, Nicole, Starkstein, Sergio E., Merello, Marcelo
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley 2020
Materias:
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/10123
Aporte de:
id I33-R139123456789-10123
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic TRASTORNOS DEL MOVIMIENTO
PSICOSIS
DELIRIO
ALUCINACIONES
PSIQUIATRIA
spellingShingle TRASTORNOS DEL MOVIMIENTO
PSICOSIS
DELIRIO
ALUCINACIONES
PSIQUIATRIA
Rossi, Malco Damián
Farcy, Nicole
Starkstein, Sergio E.
Merello, Marcelo
Nosology and phenomenology of psychosis in movement disorders
topic_facet TRASTORNOS DEL MOVIMIENTO
PSICOSIS
DELIRIO
ALUCINACIONES
PSIQUIATRIA
description Background: Psychotic symptoms, such as delusions and hallucinations, are part of the clinical picture of several conditions presenting movement disorders. Phenomenology and epidemiology of psychosis in Parkinson's disease have received wide attention; however, the presence of psychosis in other movement disorders is, comparatively, less well known. Objectives: To review psychotic symptoms present in different movement disorders. Methods: A comprehensive and structured literature search was performed to identify and analyze data on patients with movement disorders and comorbid psychosis. Results: In monogenic parkinsonisms, such as PARK‐GBA, PARK‐LRRK2, and PARK‐SNCA, visual hallucinations related to dopamine replacement therapy are frequent as well as are delusions in PARK‐LRRK2 and PARK‐SNCA, but not in PARK‐GBA. Different types of delusions and hallucinations are found in Huntington's disease and other choreic disorders. In Tourette's syndrome, paranoid delusions as well as visual, olfactory, and auditory hallucinations have been described, which usually develop after an average of 10 years of disease. Delusions in ataxias are more frequent in ATX‐TBP, ATX‐ATN1, and ATX‐ATXN3, whereas it is rare in Friedreich's ataxia. Psychosis is also a prominent and frequent clinical feature in Fahr's disease, Wilson's disease, neurodegeneration with brain iron accumulation, and some lysosomal storage disorders, whereas it is uncommon in atypical parkinsonisms and dystonia. Psychosis usually occurs at late disease stages, but may appear as onset symptoms of the disease, especially in Wilson's disease, Huntington's disease, late‐onset Tays‐Sachs, and Niemann‐Pick. Conclusion: Psychosis is a frequent comorbidity in most hyper‐ and hypokinetic movement disorders. Appropriate recognition is relevant both in the early and late disease stages.
format Artículo
author Rossi, Malco Damián
Farcy, Nicole
Starkstein, Sergio E.
Merello, Marcelo
author_facet Rossi, Malco Damián
Farcy, Nicole
Starkstein, Sergio E.
Merello, Marcelo
author_sort Rossi, Malco Damián
title Nosology and phenomenology of psychosis in movement disorders
title_short Nosology and phenomenology of psychosis in movement disorders
title_full Nosology and phenomenology of psychosis in movement disorders
title_fullStr Nosology and phenomenology of psychosis in movement disorders
title_full_unstemmed Nosology and phenomenology of psychosis in movement disorders
title_sort nosology and phenomenology of psychosis in movement disorders
publisher Wiley
publishDate 2020
url https://repositorio.uca.edu.ar/handle/123456789/10123
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AT farcynicole nosologyandphenomenologyofpsychosisinmovementdisorders
AT starksteinsergioe nosologyandphenomenologyofpsychosisinmovementdisorders
AT merellomarcelo nosologyandphenomenologyofpsychosisinmovementdisorders
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