Response to Letter to the Editor “On the targets of fluoxetine”

We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the...

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Detalles Bibliográficos
Autores principales: Di Rosso, María Emilia, Palumbo, María Laura, Genaro, Ana María
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2025
Materias:
FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/19332
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-19332
record_format dspace
spelling I33-R139-123456789-193322025-02-08T05:01:50Z Response to Letter to the Editor “On the targets of fluoxetine” Di Rosso, María Emilia Palumbo, María Laura Genaro, Ana María FARMACOLOGIA ANTIDEPRESIVOS FLUOXETINA RECEPTORES DE SEROTONINA We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described. 2025-02-07T18:41:52Z 2025-02-07T18:41:52Z 2016 Artículo https://repositorio.uca.edu.ar/handle/123456789/19332 10.1016/j.phrs.2016.06.003 eng Atribución-NoComercial-CompartirIgual 4.0 Internacional http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Elsevier Pharmacological Research. 113, 2016.
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
spellingShingle FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
Di Rosso, María Emilia
Palumbo, María Laura
Genaro, Ana María
Response to Letter to the Editor “On the targets of fluoxetine”
topic_facet FARMACOLOGIA
ANTIDEPRESIVOS
FLUOXETINA
RECEPTORES DE SEROTONINA
description We read the Letter to the Editor entitled “On the targets of Flu-oxetine” by James M. Brimson and Stephen T. Safrany referred to our review entitled “Immunomodulatory effects of fluoxetine: Anew potential pharmacological action for a classic antidepressantdrug?”.The authors consider that many of the effects described forfluoxetine could be due to the activation of sigma-1 receptorsuggesting that this receptor could be the “Novel receptor” on lym-phocytes proposed in our review. While sigma receptors activationis mainly known for their effect on the nervous system, the presence of this receptor on non-neuronal tissues, including immunesystem has been described.
format Artículo
author Di Rosso, María Emilia
Palumbo, María Laura
Genaro, Ana María
author_facet Di Rosso, María Emilia
Palumbo, María Laura
Genaro, Ana María
author_sort Di Rosso, María Emilia
title Response to Letter to the Editor “On the targets of fluoxetine”
title_short Response to Letter to the Editor “On the targets of fluoxetine”
title_full Response to Letter to the Editor “On the targets of fluoxetine”
title_fullStr Response to Letter to the Editor “On the targets of fluoxetine”
title_full_unstemmed Response to Letter to the Editor “On the targets of fluoxetine”
title_sort response to letter to the editor “on the targets of fluoxetine”
publisher Elsevier
publishDate 2025
url https://repositorio.uca.edu.ar/handle/123456789/19332
work_keys_str_mv AT dirossomariaemilia responsetolettertotheeditoronthetargetsoffluoxetine
AT palumbomarialaura responsetolettertotheeditoronthetargetsoffluoxetine
AT genaroanamaria responsetolettertotheeditoronthetargetsoffluoxetine
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