First total synthesis of (+)-Neplanocin B
(+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Artículo publishedVersion |
| Publicado: |
2005
|
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_Comin http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_14246376_v2005_n12_p205_Comin_oai |
| Aporte de: |
| id |
I28-R145-paper_14246376_v2005_n12_p205_Comin_oai |
|---|---|
| record_format |
dspace |
| spelling |
I28-R145-paper_14246376_v2005_n12_p205_Comin_oai2020-10-19 Comin, M.J. Pellegrinet, S.C. Rodriguez, J.B. 2005 (+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT. Fil:Comin, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. application/pdf http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_Comin info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar Arkivoc 2005;2005(12):205-213 6-oxabicyclo[3.1.0]hexane Ampullariella regularis Carbocyclic nucleosides Conformationally locked nucleosides Neplanocin B First total synthesis of (+)-Neplanocin B info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_14246376_v2005_n12_p205_Comin_oai |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-145 |
| collection |
Repositorio Digital de la Universidad de Buenos Aires (UBA) |
| topic |
6-oxabicyclo[3.1.0]hexane Ampullariella regularis Carbocyclic nucleosides Conformationally locked nucleosides Neplanocin B |
| spellingShingle |
6-oxabicyclo[3.1.0]hexane Ampullariella regularis Carbocyclic nucleosides Conformationally locked nucleosides Neplanocin B Comin, M.J. Pellegrinet, S.C. Rodriguez, J.B. First total synthesis of (+)-Neplanocin B |
| topic_facet |
6-oxabicyclo[3.1.0]hexane Ampullariella regularis Carbocyclic nucleosides Conformationally locked nucleosides Neplanocin B |
| description |
(+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT. |
| format |
Artículo Artículo publishedVersion |
| author |
Comin, M.J. Pellegrinet, S.C. Rodriguez, J.B. |
| author_facet |
Comin, M.J. Pellegrinet, S.C. Rodriguez, J.B. |
| author_sort |
Comin, M.J. |
| title |
First total synthesis of (+)-Neplanocin B |
| title_short |
First total synthesis of (+)-Neplanocin B |
| title_full |
First total synthesis of (+)-Neplanocin B |
| title_fullStr |
First total synthesis of (+)-Neplanocin B |
| title_full_unstemmed |
First total synthesis of (+)-Neplanocin B |
| title_sort |
first total synthesis of (+)-neplanocin b |
| publishDate |
2005 |
| url |
http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_Comin http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_14246376_v2005_n12_p205_Comin_oai |
| work_keys_str_mv |
AT cominmj firsttotalsynthesisofneplanocinb AT pellegrinetsc firsttotalsynthesisofneplanocinb AT rodriguezjb firsttotalsynthesisofneplanocinb |
| _version_ |
1766026768262627328 |