Mechanistic studies on δ-aminolevulinic acid uptake and efflux in a mammary adenocarcinoma cell line

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δ-aminolevulinic acid (ALA) is the precursor in the biosynthesis of porphyrins. The knowledge of both the regulation of ALA entrance and efflux from the cells and the control of porphyrin biosynthesis is essential to improve ALA-mediated photodynamic therapy. In this work, we studied the regulation...

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Detalles Bibliográficos
Autores principales: Correa García, S., Casas, A., Perotti, C., Batlle, A., Bermúdez Moretti, M.
Formato: Artículo publishedVersion
Publicado: 2003
Materias:
δ-aminolevulinic acid
ALA efflux
ALA uptake
Photodynamic therapy
4 aminobutyric acid
aminolevulinic acid
heme derivative
porphobilinogen
porphyrin
succinylacetone
animal cell
article
breast adenocarcinoma
cancer cell culture
cell transport
controlled study
diffusion
heme synthesis
mouse
nonhuman
photodynamic therapy
priority journal
protein function
protein protein interaction
protein transport
temperature dependence
Adenocarcinoma
Aminolevulinic Acid
Animals
gamma-Aminobutyric Acid
Mammary Neoplasms, Animal
Mice
Photochemotherapy
Photosensitizing Agents
Porphyrins
Tumor Cells, Cultured
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00070920_v89_n1_p173_CorreaGarcia
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00070920_v89_n1_p173_CorreaGarcia_oai
Aporte de:
Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

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