T 06.pmd

Porcine placenta is epitheliochorial, diffuse, folded, adecidua, and non invasive, and express adhesion molecules different. Integrins are glycoproteins composed of ? and ? subunits that govern cellular interactions with the extracellular matrix. Recent studies showed that integrins have been involv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Williamson, D.M., Koncurat, M.A.
Formato:	Artículo publishedVersion
Lenguaje:	Español
Publicado:	Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. 2009
Materias:	integrinas placenta epiteliocorial gestación cerdos integrins epitheliochorial placenta pregnancy pigs
Acceso en línea:	http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4970 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4970.dir/4970.PDF
Aporte de:	Repositorio Digital de la Universidad de Buenos Aires (UBA) de Universidad de Buenos Aires

id	I28-R145-HWA_4970
record_format	dspace
spelling	I28-R145-HWA_49702024-11-05 T 06.pmd Porcine placenta is epitheliochorial, diffuse, folded, adecidua, and non invasive, and express adhesion molecules different. Integrins are glycoproteins composed of ? and ? subunits that govern cellular interactions with the extracellular matrix. Recent studies showed that integrins have been involved in implantation events in several species. The aim of this study was to compare the expression of ?v?3, ?3 and ?1 during placentation porcine. Placental tissue from porcine female of 37, 60, 70, 80 and 114 days of gestation, and empty uterus were used. The detection of the integrins was analyzed by indirect immunoperoxidase. During placentation avb3 was expressed abundantly, decreasing from day 80 on. The integrins ?1 was the one that marked great positivity in all placental tissues studied, decreasing it expression only at the end of de gestation. The ?3 subunits was not expressed in endometrials glands in none of the gestational periods studied. The results of this study remark the importance of the expression of integrins during the porcine placentation, particularly ?1, during the gestation to allow the redesigning of the placental villi and ?3 from interareolares zones.\n Fil: Williamson, D.M. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento de Ciencias Básicas. Cátedra Biología General . La Pampa, Argentina Fil: Williamson, D.M. CONICET. Argentina Fil: Koncurat, M.A. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias. Departamento de Ciencias Básicas. Cátedra Biología General . La Pampa, Argentina Williamson, D.M. Koncurat, M.A. 2009 La placenta porcina es epiteliocorial, adecidua, plegada, difusa y no invasiva, por lo que expresa moléculas de adhesión que posibilitan la formación de la interfase feto/materna. Las integrinas son glicoproteínas que gobiernan las interacciones celulares con la matriz extracelular y participan en la implantación de varias especies. El objetivo de éste estudio fue analizar y comparar la expresión de e ?v?3, ?3 y ?1 a fin de detectar la existencia de un patrón de expresión diferencial durante la placentación porcina. Se utilizaron placentas porcinas de ± 37, 60, 70, 80 y 114 días de gestación y útero vacío. La presencia de integrinas se determinó por inmunoperoxidasa indirecta. Durante la placentación ?v?3 se expresó cuantiosamente, disminuyendo a partir de los 80 días. La integrina ?1 fue la que mayor positividad marcó en todos los tejidos placentarios estudiados, disminuyendo su expresión solo al final de la gestación. La subunidad ?3 no se expresó en glándulas endometriales en ninguno de los períodos gestacionales estudiados. Los resultados de este estudio remarcan la importancia de la expresión de las integrinas durante la placentación porcina, particularmente ?1 , en el transcurso de la gestación para permitir la remodelación de las vellosidades placentarias y ?3 de las zonas interareolares. application/pdf 1514-6634 (impreso) 1668-3498 (en línea) integrinas placenta epiteliocorial gestación cerdos integrins epitheliochorial placenta pregnancy pigs spa Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ InVet, vol. 11, nº1 Expresión de la integrina ?v?3 y de las subunidades de integrinas ?3 y ?1 durante la placentación porcina. Expression of ?v?3, and subunits ?3 and ?1 during porcine placentation info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4970 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4970.dir/4970.PDF
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-145
collection	Repositorio Digital de la Universidad de Buenos Aires (UBA)
language	Español
orig_language_str_mv	spa
topic	integrinas placenta epiteliocorial gestación cerdos integrins epitheliochorial placenta pregnancy pigs
spellingShingle	integrinas placenta epiteliocorial gestación cerdos integrins epitheliochorial placenta pregnancy pigs Williamson, D.M. Koncurat, M.A. T 06.pmd
topic_facet	integrinas placenta epiteliocorial gestación cerdos integrins epitheliochorial placenta pregnancy pigs
description	Porcine placenta is epitheliochorial, diffuse, folded, adecidua, and non invasive, and express adhesion molecules different. Integrins are glycoproteins composed of ? and ? subunits that govern cellular interactions with the extracellular matrix. Recent studies showed that integrins have been involved in implantation events in several species. The aim of this study was to compare the expression of ?v?3, ?3 and ?1 during placentation porcine. Placental tissue from porcine female of 37, 60, 70, 80 and 114 days of gestation, and empty uterus were used. The detection of the integrins was analyzed by indirect immunoperoxidase. During placentation avb3 was expressed abundantly, decreasing from day 80 on. The integrins ?1 was the one that marked great positivity in all placental tissues studied, decreasing it expression only at the end of de gestation. The ?3 subunits was not expressed in endometrials glands in none of the gestational periods studied. The results of this study remark the importance of the expression of integrins during the porcine placentation, particularly ?1, during the gestation to allow the redesigning of the placental villi and ?3 from interareolares zones.\n
format	Artículo Artículo publishedVersion
author	Williamson, D.M. Koncurat, M.A.
author_facet	Williamson, D.M. Koncurat, M.A.
author_sort	Williamson, D.M.
title	T 06.pmd
title_short	T 06.pmd
title_full	T 06.pmd
title_fullStr	T 06.pmd
title_full_unstemmed	T 06.pmd
title_sort	t 06.pmd
publisher	Universidad de Buenos Aires. Facultad de Ciencias Veterinarias.
publishDate	2009
url	http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4970 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4970.dir/4970.PDF
work_keys_str_mv	AT williamsondm t06pmd AT koncuratma t06pmd AT williamsondm expresiondelaintegrinav3ydelassubunidadesdeintegrinas3y1durantelaplacentacionporcina AT koncuratma expresiondelaintegrinav3ydelassubunidadesdeintegrinas3y1durantelaplacentacionporcina AT williamsondm expressionofv3andsubunits3and1duringporcineplacentation AT koncuratma expressionofv3andsubunits3and1duringporcineplacentation
_version_	1824359807807651840

T 06.pmd

Ejemplares similares