In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins

A comparative study was conducted between the antibacterial activity of honey and cephalexin against a strain of Escherichia coli and honey and cefquinome against a strain of Staphylococcus aureus by modified time-kill-curves essays. In all trials, the maximum antibacterial activity of honey was obs...

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Autores principales: DELL'ELCE, Antonella, AGUIRRE, Soledad, PATRICELLI, Paula, FORMENTINI, Enrique
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2018
Materias:
honey
antibacterial activity
Escherichia coli
Staphylococcus aureus
miel
actividad bactericida
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/7160
Aporte de:
Biblioteca Virtual - Publicaciones (UNL) de Universidad Nacional del Litoral
id I26-R133-article-7160
record_format ojs
spelling I26-R133-article-71602019-05-24T11:50:45Z In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins Actividad bactericida in vitro de miel sobre Escherichia coli y Staphylococcus aureus. Comparación con la actividad de cefalosporinas. DELL'ELCE, Antonella AGUIRRE, Soledad PATRICELLI, Paula FORMENTINI, Enrique honey antibacterial activity Escherichia coli Staphylococcus aureus Escherichia coli Staphylococcus aureus miel actividad bactericida A comparative study was conducted between the antibacterial activity of honey and cephalexin against a strain of Escherichia coli and honey and cefquinome against a strain of Staphylococcus aureus by modified time-kill-curves essays. In all trials, the maximum antibacterial activity of honey was observed at a dilution of 50% v/v. Regarding the comparative efficacy between honey and antibiotics, it was observed that against E. coli, cephalexin achieved a reduction in viable bacteria count compatible with a bactericidal effect (<500 cfu/mL), while honey did not overcome this breakpoint. The opposite was observed for S. aureus, where honey achieved a reduction in the viable bacteria count compatible with a bacterial eradication effect (<50 cfu/mL) with respect to the bactericidal effect obtained with cefquinome (<500 cfu/mL). These preliminary results corroborate the need to revalue the antibacterial activity of natural products, whose efficacy - although empirically - was already known since antiquity and was forgotten after the appearance of antibiotics. Se realizó un estudio comparativo entre la actividad antibacteriana de miel y cefalexina sobre una cepa de Escherichia coli y de miel y cefquinoma sobre una cepa de Staphylococcus aureus mediante ensayos de curva de muerte modificada. En todos los ensayos, la máxima actividad antibacteriana de la miel se observó a una dilución del 50% v/v. Respecto de la eficacia comparativa entre la miel y los antibióticos, se observó que sobre E. coli, cefalexina logró una reducción del conteo de bacterias viables compatible con un efecto bactericida (< 500 ufc/mL), mientras que la miel no logró superar este punto de corte. Lo opuesto se observó para S. aureus, donde la miel logró una reducción del conteo de bacterias viables compatible con un efecto de erradicación bacteriana (< 50 ufc/mL) respecto del efecto bactericida obtenido con cefquinoma (< 500 ufc/mL). Estos resultados preliminares, corroboran la necesidad de revalorar la actividad antibacteriana de productos naturales, cuya eficacia -aunque de manera empírica- ya era conocida desde la antigüedad y que fuera olvidada a partir de la aparición de los antibióticos.   Universidad Nacional del Litoral 2018-03-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Comunicación corta Short communication application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/7160 10.14409/favecv.v17i1.7160 FAVE Sección Ciencias Veterinarias; Vol. 17 Núm. 1 (2018): FAVE Sección Ciencias Veterinarias; 12-17 FAVE Sección Ciencias Veterinarias; Vol. 17 No. 1 (2018): FAVE Sección Ciencias Veterinarias; 12-17 FAVE Sección Ciencias Veterinarias; v. 17 n. 1 (2018): FAVE Sección Ciencias Veterinarias; 12-17 2362-5589 1666-938X 10.14409/favecv.v17i1 spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/7160/10374 Derechos de autor 2018 Antonella DELL'ELCE, Soledad AGUIRRE, Paula PATRICELLI, Enrique FORMENTINI
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic honey
antibacterial activity
Escherichia coli
Staphylococcus aureus
Escherichia coli
Staphylococcus aureus
miel
actividad bactericida
spellingShingle honey
antibacterial activity
Escherichia coli
Staphylococcus aureus
Escherichia coli
Staphylococcus aureus
miel
actividad bactericida
DELL'ELCE, Antonella
AGUIRRE, Soledad
PATRICELLI, Paula
FORMENTINI, Enrique
In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
topic_facet honey
antibacterial activity
Escherichia coli
Staphylococcus aureus
Escherichia coli
Staphylococcus aureus
miel
actividad bactericida
author DELL'ELCE, Antonella
AGUIRRE, Soledad
PATRICELLI, Paula
FORMENTINI, Enrique
author_facet DELL'ELCE, Antonella
AGUIRRE, Soledad
PATRICELLI, Paula
FORMENTINI, Enrique
author_sort DELL'ELCE, Antonella
title In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
title_short In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
title_full In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
title_fullStr In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
title_full_unstemmed In vitro bactericidal activity of honey against Escherichia coli and Staphylococcus aureus. Comparison with the activity of cephalosporins
title_sort in vitro bactericidal activity of honey against escherichia coli and staphylococcus aureus. comparison with the activity of cephalosporins
description A comparative study was conducted between the antibacterial activity of honey and cephalexin against a strain of Escherichia coli and honey and cefquinome against a strain of Staphylococcus aureus by modified time-kill-curves essays. In all trials, the maximum antibacterial activity of honey was observed at a dilution of 50% v/v. Regarding the comparative efficacy between honey and antibiotics, it was observed that against E. coli, cephalexin achieved a reduction in viable bacteria count compatible with a bactericidal effect (<500 cfu/mL), while honey did not overcome this breakpoint. The opposite was observed for S. aureus, where honey achieved a reduction in the viable bacteria count compatible with a bacterial eradication effect (<50 cfu/mL) with respect to the bactericidal effect obtained with cefquinome (<500 cfu/mL). These preliminary results corroborate the need to revalue the antibacterial activity of natural products, whose efficacy - although empirically - was already known since antiquity and was forgotten after the appearance of antibiotics.
publisher Universidad Nacional del Litoral
publishDate 2018
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/7160
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first_indexed 2023-07-05T23:06:57Z
last_indexed 2023-07-05T23:06:57Z
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