The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.

In pharmacology, hormesis is defined as the high efficacy of a drug at low doses and a decrease of efficacy at higher doses. In this study, the hormesis phenomenon on the antibacterial activity of honey was assessed. The activity of four honeys (A, D, C and D) were checked by agar plate diffusion me...

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Autor principal: Castromán, R
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2021
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Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10931
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spelling I26-R133-article-109312023-09-15T10:33:20Z The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus. DILUCIÓN DE MIEL EN AGUA INDUCE HORMESIS EN LA ACTIVIDAD ANTIBACTERIANA SOBRE Staphylococcus aureus. Castromán, R Honey, Antibacterial activity, Staphylococcus aureus, Hormesis Miel, Actividad antibacteriana, Staphylococcus aureus, Hormesis In pharmacology, hormesis is defined as the high efficacy of a drug at low doses and a decrease of efficacy at higher doses. In this study, the hormesis phenomenon on the antibacterial activity of honey was assessed. The activity of four honeys (A, D, C and D) were checked by agar plate diffusion method using S. aureus (ATCC 29213) as the test organism. Each honey was tested as follows; on the surface of an agar plate, five stainless steel cylinders with a diameter of 8,14 mm were radially disposed. Onto each cylinder 0,1 mL of the sample honey diluted in water at 50 – 25 - 12,5 -6,25 and 3,125 % v/v were placed. Plates were incubated at 35°C during 24 h. The surface of the cylinder diameter was set as reference antibacterial activity (Ra). The antibacterial activity of each honey was quantitated by the relationship between the surface of the inhibitory zone (Iz) and the surface of the reference activity (Iz/Ra). An increase in the antibacterial activity was observed at a concentration of water greater than 50% in honeys B and C. This hormetic behavior could be considered as indicator of the quality of the antibacterial activity of these honeys.   Universidad Nacional del Litoral 2021-12-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10931 10.14409/favecv.v19isuplemento.10931 FAVE Sección Ciencias Veterinarias; Vol. 19 Núm. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; Vol. 19 No. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; v. 19 n. suplemento (2021): FAVE Sección Ciencias Veterinarias 2362-5589 1666-938X 10.14409/favecv.v19isuplemento spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10931/14949 Derechos de autor 2021 R Castromán
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic Honey, Antibacterial activity, Staphylococcus aureus, Hormesis
Miel, Actividad antibacteriana, Staphylococcus aureus, Hormesis
spellingShingle Honey, Antibacterial activity, Staphylococcus aureus, Hormesis
Miel, Actividad antibacteriana, Staphylococcus aureus, Hormesis
Castromán, R
The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
topic_facet Honey, Antibacterial activity, Staphylococcus aureus, Hormesis
Miel, Actividad antibacteriana, Staphylococcus aureus, Hormesis
author Castromán, R
author_facet Castromán, R
author_sort Castromán, R
title The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
title_short The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
title_full The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
title_fullStr The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
title_full_unstemmed The dilution of honey in water induces hormesis on its antibacterial activity against Staphylococcus aureus.
title_sort dilution of honey in water induces hormesis on its antibacterial activity against staphylococcus aureus.
description In pharmacology, hormesis is defined as the high efficacy of a drug at low doses and a decrease of efficacy at higher doses. In this study, the hormesis phenomenon on the antibacterial activity of honey was assessed. The activity of four honeys (A, D, C and D) were checked by agar plate diffusion method using S. aureus (ATCC 29213) as the test organism. Each honey was tested as follows; on the surface of an agar plate, five stainless steel cylinders with a diameter of 8,14 mm were radially disposed. Onto each cylinder 0,1 mL of the sample honey diluted in water at 50 – 25 - 12,5 -6,25 and 3,125 % v/v were placed. Plates were incubated at 35°C during 24 h. The surface of the cylinder diameter was set as reference antibacterial activity (Ra). The antibacterial activity of each honey was quantitated by the relationship between the surface of the inhibitory zone (Iz) and the surface of the reference activity (Iz/Ra). An increase in the antibacterial activity was observed at a concentration of water greater than 50% in honeys B and C. This hormetic behavior could be considered as indicator of the quality of the antibacterial activity of these honeys.  
publisher Universidad Nacional del Litoral
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10931
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first_indexed 2023-07-05T23:06:06Z
last_indexed 2024-08-13T20:37:33Z
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