Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study

Introduction and objectives: Periodontal disease (periodontitis) and atheromatous disease share not only risk factors such as smoking and diabetes, but also a complex multifactorial process of chronic inflammation stimulating mediators that accelerate endothelial dysfunction and/or mechanisms of cr...

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Autores principales: Olavegogeascoechea, Pablo Alejandro, Allevato, Jose A., Olavegogeascoechea, Facundo N., Contreras, Pablo, Thalasselis, Demetrio C., Valenzuela, Gabriela, Urdiales, Pedro L., Brusca, Maria I.
Formato: Articulo article acceptedVersion
Lenguaje:Inglés
Publicado: MedCrave Group 2017
Materias:
Periodontal disease
Periodontitis
Acute vascular events
Acute coronary syndrome
Ciencias Biomédicas
Acceso en línea:https://rdi.uncoma.edu.ar/handle/uncomaid/18209
Aporte de:
Repositorio Institucional UNCo de Universidad Nacional del Comahue
id I22-R178-uncomaid-18209
record_format dspace
spelling I22-R178-uncomaid-182092025-03-06T14:21:57Z Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study Olavegogeascoechea, Pablo Alejandro Allevato, Jose A. Olavegogeascoechea, Facundo N. Contreras, Pablo Thalasselis, Demetrio C. Valenzuela, Gabriela Urdiales, Pedro L. Brusca, Maria I. Periodontal disease Periodontitis Acute vascular events Acute coronary syndrome Ciencias Biomédicas Introduction and objectives: Periodontal disease (periodontitis) and atheromatous disease share not only risk factors such as smoking and diabetes, but also a complex multifactorial process of chronic inflammation stimulating mediators that accelerate endothelial dysfunction and/or mechanisms of crossreacting antibodies against the periodontal flora and endothelial cell proteins; this may explain the association between both pathologies. The aim of our study was to add evidence about the relationship between periodontal disease (periodontitis) and vascular disease, using acute vascular events as the primary endpoint. Methods: A case-control study was conducted. A total of 30 cases and 32 controls were included in a non-randomized selection. Results: The presence of periodontal disease was significantly higher in cases than it was in controls (70 % vs. 40 %; OR [95 % CI]: 3.41 [1.19-9.76]; p=0.02). Also, plaque and gingival indexes were significantly higher in cases (PI: 1.74 ± 0.64 vs. 0.99 ± 0.69, respectively, p <0.01; GI: 1.61 ± 0.66 vs. 0.98 ± 0.55, respectively, p <0.01). Conclusion: This study demonstrates a strong association between periodontal disease and acute vascular events, the former having an even greater impact than traditional risk factors. Fil: Olavegogeascoechea, Pablo A. Universidad Nacional del Comahue. Facultad de Medicina. Departamento de Salud Colectiva; Argentina. Fil: Olavegogeascoechea, Pablo A. Universidad Abierta Interamericana. Facultad de Odontología; Argentina. Fil: Allevato, Jose A. Universidad Nacional del Comahue. Facultad de Medicina. Departamento de Salud Colectiva; Argentina. Fil: Olavegogeascoechea, Facundo N. Universidad Nacional del Comahue. Facultad de Medicina. Departamento de Salud Colectiva; Argentina. Fil: Contreras, Pablo. Fundación Médica de Río Negro y Neuquén. Departamento de Cardiología; Argentina. Fil: Thalasselis, Demetrio C. Fundación Médica de Río Negro y Neuquén. Departamento de Cardiología; Argentina. Fil: Valenzuela, Gabriela. Fundación Médica de Río Negro y Neuquén. Departamento de Cardiología; Argentina. Fil: Urdiales, Pedro L. Fundación Médica de Río Negro y Neuquén. Departamento de Cardiología; Argentina. Fil: Brusca, Maria I. Universidad Abierta Interamericana. Facultad de Odontología; Argentina. 2017-07-01 2024-10-04T13:50:07Z 2024-10-04T13:50:07Z Articulo article acceptedVersion 2373-4345 https://rdi.uncoma.edu.ar/handle/uncomaid/18209 eng https://medcraveonline.com/JDHODT/ Atribución-NoComercial-CompartirIgual 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf pp.1-6 application/pdf MedCrave Group Journal of Dental Health, Oral Disorders & Therapy. Volume 7 Issue 5 - (2017)
institution Universidad Nacional del Comahue
institution_str I-22
repository_str R-178
collection Repositorio Institucional UNCo
language Inglés
topic Periodontal disease
Periodontitis
Acute vascular events
Acute coronary syndrome
Ciencias Biomédicas
spellingShingle Periodontal disease
Periodontitis
Acute vascular events
Acute coronary syndrome
Ciencias Biomédicas
Olavegogeascoechea, Pablo Alejandro
Allevato, Jose A.
Olavegogeascoechea, Facundo N.
Contreras, Pablo
Thalasselis, Demetrio C.
Valenzuela, Gabriela
Urdiales, Pedro L.
Brusca, Maria I.
Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
topic_facet Periodontal disease
Periodontitis
Acute vascular events
Acute coronary syndrome
Ciencias Biomédicas
description Introduction and objectives: Periodontal disease (periodontitis) and atheromatous disease share not only risk factors such as smoking and diabetes, but also a complex multifactorial process of chronic inflammation stimulating mediators that accelerate endothelial dysfunction and/or mechanisms of crossreacting antibodies against the periodontal flora and endothelial cell proteins; this may explain the association between both pathologies. The aim of our study was to add evidence about the relationship between periodontal disease (periodontitis) and vascular disease, using acute vascular events as the primary endpoint. Methods: A case-control study was conducted. A total of 30 cases and 32 controls were included in a non-randomized selection. Results: The presence of periodontal disease was significantly higher in cases than it was in controls (70 % vs. 40 %; OR [95 % CI]: 3.41 [1.19-9.76]; p=0.02). Also, plaque and gingival indexes were significantly higher in cases (PI: 1.74 ± 0.64 vs. 0.99 ± 0.69, respectively, p <0.01; GI: 1.61 ± 0.66 vs. 0.98 ± 0.55, respectively, p <0.01). Conclusion: This study demonstrates a strong association between periodontal disease and acute vascular events, the former having an even greater impact than traditional risk factors.
format Articulo
article
acceptedVersion
author Olavegogeascoechea, Pablo Alejandro
Allevato, Jose A.
Olavegogeascoechea, Facundo N.
Contreras, Pablo
Thalasselis, Demetrio C.
Valenzuela, Gabriela
Urdiales, Pedro L.
Brusca, Maria I.
author_facet Olavegogeascoechea, Pablo Alejandro
Allevato, Jose A.
Olavegogeascoechea, Facundo N.
Contreras, Pablo
Thalasselis, Demetrio C.
Valenzuela, Gabriela
Urdiales, Pedro L.
Brusca, Maria I.
author_sort Olavegogeascoechea, Pablo Alejandro
title Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
title_short Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
title_full Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
title_fullStr Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
title_full_unstemmed Relationship between Periodontal Disease (Periodontitis) and Acute Vascular Events a Case-Control Study Enperiva Study
title_sort relationship between periodontal disease (periodontitis) and acute vascular events a case-control study enperiva study
publisher MedCrave Group
publishDate 2017
url https://rdi.uncoma.edu.ar/handle/uncomaid/18209
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