Structural Basis of Outstanding Multivalent Effects in Jack Bean α-Mannosidase Inhibition
Multivalent design of glycosidase inhibitors is a promising strategy for the treatment of diseases involving enzymatic hydrolysis of glycosidic bonds in carbohydrates. An essential prerequisite for successful applications is the atomic‐level understanding of how outstanding binding enhancement occur...
| Autores principales: | Howard, Eduardo Ignacio, Cousido Siah, Alexandra, Lepage, Mathieu L., Schneider, Jérémy P., Bodlenner, Anne, Mitschler, André, Meli, Alessandra, Izzo, Irene, Álvarez, Hugo Ariel, Podjarny, Alberto, Compain, Philippe |
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| Formato: | Articulo Preprint |
| Lenguaje: | Inglés |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/96218 https://ri.conicet.gov.ar/11336/87935 http://doi.wiley.com/10.1002/anie.201801202 |
| Aporte de: |
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