Determination of thermodynamic binding constants by affinity capillary electrophoresis

A strategy to study thermodynamic binding constants by affinity capillary electrophoresis (ACE) is presented. In order to simplify mathematical treatment, analogy with acid-base dissociation equilibrium is proposed: instead of ligand concentration [X], negative logarithm of ligand concentration (or...

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Autores principales: Lancioni, Carlina, Keunchkarian, Sonia, Castells, Cecilia Beatriz Marta, Gagliardi, Leonardo Gabriel
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2019
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/128708
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