Understanding the role of apolipoprotein A-I in atherosclerosis : Post-translational modifications synergize dysfunction?

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Background: The identification of dysfunctional human apolipoprotein A-I (apoA-I) in atherosclerotic plaques suggests that protein structure and function may be hampered under a chronic pro inflammatory scenario. Moreover, the fact that natural mutants of this protein elicit severe cardiovascular di...

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Detalles Bibliográficos
Autores principales: Díaz Ludovico, Ivo, Gisonno, Romina Antonela, González, Marina Cecilia, Garda, Horacio Alberto, Ramella, Nahuel Alberto, Tricerri, María Alejandra
Formato: Articulo Preprint
Lenguaje:Español
Publicado: 2020
Materias:
Ciencias Médicas
Loss function
Folding (chemistry)
Function (biology)
Mutant
Chemistry
Native state
Protein structure
Mutation
Apolipoprotein b
Cell biology
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/124884
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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