Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules

An synthetic strategy for the generation of a variety of biaryl and related derivatives, based on Suzuki– Miyaura coupling using immobilized boronic acid, is described. The importance of the methodology was demonstrated by its further application to biologically interesting compounds such as 4-bia...

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Detalles Bibliográficos
Autores principales:	Martinez-Amezaga, Maitena, Delpiccolo, Carina M. L., Mata, Ernesto Gabino
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	Royal Society of Chemistry 2020
Materias:	Boronic Acids Suzuki–Miyaura Coupling Solid-Phase Organic Synthesis
Acceso en línea:	http://hdl.handle.net/2133/19545 http://hdl.handle.net/2133/19545
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

id	I15-R121-2133-19545
record_format	dspace
institution	Universidad Nacional de Rosario
institution_str	I-15
repository_str	R-121
collection	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR)
language	Inglés
orig_language_str_mv	eng
topic	Boronic Acids Suzuki–Miyaura Coupling Solid-Phase Organic Synthesis
spellingShingle	Boronic Acids Suzuki–Miyaura Coupling Solid-Phase Organic Synthesis Martinez-Amezaga, Maitena Delpiccolo, Carina M. L. Mata, Ernesto Gabino Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
topic_facet	Boronic Acids Suzuki–Miyaura Coupling Solid-Phase Organic Synthesis
description	An synthetic strategy for the generation of a variety of biaryl and related derivatives, based on Suzuki– Miyaura coupling using immobilized boronic acid, is described. The importance of the methodology was demonstrated by its further application to biologically interesting compounds such as 4-biaryl-blactams, descripted as cholesterol absorption inhibitors and anti-MRSA active agents, neoflavonoids, imidazoles, isoxazolines, among others.
format	article artículo publishedVersion
author	Martinez-Amezaga, Maitena Delpiccolo, Carina M. L. Mata, Ernesto Gabino
author_facet	Martinez-Amezaga, Maitena Delpiccolo, Carina M. L. Mata, Ernesto Gabino
author_sort	Martinez-Amezaga, Maitena
title	Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
title_short	Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
title_full	Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
title_fullStr	Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
title_full_unstemmed	Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
title_sort	immobilized boronic acid for suzuki–miyaura coupling: application to the generation of pharmacologically relevant molecules
publisher	Royal Society of Chemistry
publishDate	2020
url	http://hdl.handle.net/2133/19545 http://hdl.handle.net/2133/19545
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bdutipo_str	Repositorios
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Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules

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