CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES

Due to the great number of commercial tests available in the market to determine urinary benzodiazepine metabolites, we decided to assess the concordance between two immunological tests available in the Toxicology lab in our hospital. Urine samples received in our lab were analyzed by both methods a...

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Autores principales: Marks, Lucrecia, Gonzalez, Ines Isabel, Suarez, Hector Andres, Rivolta, Susana Elvira
Formato: Artículo revista
Lenguaje:Español
Publicado: Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC 2019
Materias:
benzodiazepine metabolites
concordance
immunological tests
metabolitos benzodiacepinas – concordancia – test inmunológicos
metabólitos benzodiazepínicos
concordância
testes imunológicos
Acceso en línea:https://revistas.unc.edu.ar/index.php/RSD/article/view/21974
Aporte de:
Revista de Salud Pública de Universidad Nacional de Córdoba
id I10-R360-article-21974
record_format ojs
spelling I10-R360-article-219742025-04-03T12:06:03Z CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES Concordancia de dos métodos inmunológicos para la determinación de Metabolitos de Benezodiacepinas en orina CONCORDÂNCIA DE DOIS MÉTODOS IMUNOLÓGICOS PARA A DETERMINAÇÃO DE METABÓLITOS DE BENZODIACEPINAS EM URINA. Marks, Lucrecia Gonzalez, Ines Isabel Suarez, Hector Andres Rivolta, Susana Elvira benzodiazepine metabolites concordance immunological tests metabolitos benzodiacepinas – concordancia – test inmunológicos metabólitos benzodiazepínicos concordância testes imunológicos Due to the great number of commercial tests available in the market to determine urinary benzodiazepine metabolites, we decided to assess the concordance between two immunological tests available in the Toxicology lab in our hospital. Urine samples received in our lab were analyzed by both methods at the same time. Statistics tests of Kappa and Chi-Square are used for evaluation. The usefulness of these tests in cases of the diagnostic suspicion of benzodiazepine consumption in certain pathologies deserves the availability of these immunological tests since they can provide results in a short time which will let the medical professional make timely decisions regarding the problem presented by the patient. In this work we have been able to verify that both methods show good concordance (Kappa Test = 0.88) so, both can be indistinctly used for the cases presented by the Toxicology lab. Debido a la gran cantidad de test comerciales disponibles para la determinación de metabolitos de benzodiacepinas en orina en el mercado, es que decidimos evaluar la concordancia de 2 test inmunológicos, disponibles en el laboratorio de Toxicología de nuestro hospital. Las muestras de orinas recibidas en nuestro laboratorio fueron analizadas en paralelo por ambos métodos. Se aplicaran los test estadisticos de Kappa y Chi cuadrado para su evaluación. La utilidad de estos test ante la sospecha diagnóstica de consumo de benzodiacepinas en determinadas patologías, amerita la disponibilidad de estos test inmunológicos que pueden proveer en corto tiempo, un resultado que permita al profesional médico una oportuna toma de decisiones frente a la problemática con la cual arriba el paciente. En este trabajo pudimos comprobar que ambos métodos presentan muy buena concordancia (test Kappa=0,88), por lo cual son ambos test indistintamente aplicables para la casuística que presenta el Laboratorio de Toxicología. Devido ao grande número de testes comerciais disponíveis no mercado para a determinação de metabólitos de benzodiazepina na urina, decidimos avaliar a concordância de dois testes imunológicos, disponíveis no laboratório de Toxicologia de nosso hospital. As amostras de urina recebidas em nosso laboratório foram analisadas em paralelo pelos dois métodos. Os testes estatísticos Kappa e Xi quadrado serão aplicados na sua avaliação. A utilidade desses testes diante da suspeita diagnóstica do consumo de benzodiazepínicosem determinadas patologias merece a disponibilidade desses testes imunológicos que podem fornecer em pouco tempo, resultados que permitem ao profissional médico uma tomada de decisão oportuna em relação ao problema apresentado pelo paciente. Neste trabalho, pudemos verificar que ambos os métodos têm uma concordância muito boa (teste Kappa = 0,88), motivo pelo qual ambos são testes indistintamente aplicáveis ao estudo de casos apresentados pelo Laboratório de Toxicologia. Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC 2019-12-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/RSD/article/view/21974 10.31052/1853.1180.v23.n3.21974 Revista de Salud Pública; Vol. 23 Núm. 3 (2019): Revista de Salud Pública; 77-84 1852-9429 1853-1180 10.31052/1853.1180.v23.n3 spa https://revistas.unc.edu.ar/index.php/RSD/article/view/21974/28393 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-360
container_title_str Revista de Salud Pública
language Español
format Artículo revista
topic benzodiazepine metabolites
concordance
immunological tests
metabolitos benzodiacepinas – concordancia – test inmunológicos
metabólitos benzodiazepínicos
concordância
testes imunológicos
spellingShingle benzodiazepine metabolites
concordance
immunological tests
metabolitos benzodiacepinas – concordancia – test inmunológicos
metabólitos benzodiazepínicos
concordância
testes imunológicos
Marks, Lucrecia
Gonzalez, Ines Isabel
Suarez, Hector Andres
Rivolta, Susana Elvira
CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
topic_facet benzodiazepine metabolites
concordance
immunological tests
metabolitos benzodiacepinas – concordancia – test inmunológicos
metabólitos benzodiazepínicos
concordância
testes imunológicos
author Marks, Lucrecia
Gonzalez, Ines Isabel
Suarez, Hector Andres
Rivolta, Susana Elvira
author_facet Marks, Lucrecia
Gonzalez, Ines Isabel
Suarez, Hector Andres
Rivolta, Susana Elvira
author_sort Marks, Lucrecia
title CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
title_short CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
title_full CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
title_fullStr CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
title_full_unstemmed CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES
title_sort concordance of two immunological methods to determine urinary benzodiazepine metabolites
description Due to the great number of commercial tests available in the market to determine urinary benzodiazepine metabolites, we decided to assess the concordance between two immunological tests available in the Toxicology lab in our hospital. Urine samples received in our lab were analyzed by both methods at the same time. Statistics tests of Kappa and Chi-Square are used for evaluation. The usefulness of these tests in cases of the diagnostic suspicion of benzodiazepine consumption in certain pathologies deserves the availability of these immunological tests since they can provide results in a short time which will let the medical professional make timely decisions regarding the problem presented by the patient. In this work we have been able to verify that both methods show good concordance (Kappa Test = 0.88) so, both can be indistinctly used for the cases presented by the Toxicology lab.
publisher Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC
publishDate 2019
url https://revistas.unc.edu.ar/index.php/RSD/article/view/21974
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first_indexed 2024-09-03T22:26:43Z
last_indexed 2025-05-10T05:21:47Z
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