Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina
Argentina, and specifically Córdoba, have high rates of colorectal cancer (CRC), ranking second in incidence and mortality. Its occurrence correlates with environmental, biological, contextual, and lifestyle exposures. Our objective was to analyze the time series of CRC incidence and identify its as...
| Autores principales: | , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2023
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/42811 |
| Aporte de: |
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I10-R327-article-42811 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
Population-based registry Multilevel modeling Geographic Information System Registro base poblacional Modelado multinivel Sistema de Información Geográfica . |
| spellingShingle |
Population-based registry Multilevel modeling Geographic Information System Registro base poblacional Modelado multinivel Sistema de Información Geográfica . Canale , MG Stímolo, MI Muñoz, SE Díaz , MP Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| topic_facet |
Population-based registry Multilevel modeling Geographic Information System Registro base poblacional Modelado multinivel Sistema de Información Geográfica . |
| author |
Canale , MG Stímolo, MI Muñoz, SE Díaz , MP |
| author_facet |
Canale , MG Stímolo, MI Muñoz, SE Díaz , MP |
| author_sort |
Canale , MG |
| title |
Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| title_short |
Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| title_full |
Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| title_fullStr |
Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| title_full_unstemmed |
Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina |
| title_sort |
urbanization and quality of life condition the incidence of colorectal cancer in córdoba-argentina |
| description |
Argentina, and specifically Córdoba, have high rates of colorectal cancer (CRC), ranking second in incidence and mortality. Its occurrence correlates with environmental, biological, contextual, and lifestyle exposures. Our objective was to analyze the time series of CRC incidence and identify its association with urbanization and quality of life in Córdoba, Argentina (2004-2014).
A longitudinal ecological study was conducted. Age-standardized incidence rates (ASIR) (standard national and world population) by sex were calculated for Córdoba and its 26 departments for CRC (ICD-10: C18-20), using the provincial tumor registry database. The departments were grouped into three categories, according to the urban scale: High (n=2, cities >400,000 inhabitants); Intermediate (n=13, between 400,000-20,000); and Low (n=11, <20,000). The Quality of Life Index proposed by Velázquez (2010) was employed. Departmental ASIRs were mapped into quintiles. Multilevel modeling was used to estimate the effects (IRR) of sex, time (calendar year), urbanization, and quality of life on ASIRs. Software used: QGis and Stata 17.
At the provincial level, CRC ASIRs were 30.9 (95% CI: 29.9-32.0) and 24.3 (95% CI: 23.3-25.3) cases/100,000 for males and females, respectively, and did not decrease over the past decade. Maps reflected differential geospatial patterns by sex. Spatial variability (at the departmental level) indicated high heterogeneity (Var=0.29; 95% CI: 0.16-0.51). The risk of occurrence was significantly higher in males (IRR: 1.63, 95% CI: 1.53-1.76). Lower incidences of this cancer were significantly associated with better quality of life (IRR: 0.28, 95% CI: 0.16-0.47) and inversely with Intermediate urbanization (IRR: 3.65, 95% CI: 1.59-8.41) and Low urbanization (IRR: 7.4, 95% CI: 2.85-19.51).
Therefore, despite not decreasing over the past decade, the incidence of CRC, associated with urbanization and poor quality of life, remains more pronounced in the male population. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/42811 |
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I10-R327-article-428112023-10-19T21:19:04Z Urbanization and Quality of Life condition the incidence of Colorectal Cancer in Córdoba-Argentina Urbanización y Calidad de Vida condicionan la incidencia del Cáncer Colorrectal en Córdoba-Argentina . Canale , MG Stímolo, MI Muñoz, SE Díaz , MP Population-based registry Multilevel modeling Geographic Information System Registro base poblacional Modelado multinivel Sistema de Información Geográfica . Argentina, and specifically Córdoba, have high rates of colorectal cancer (CRC), ranking second in incidence and mortality. Its occurrence correlates with environmental, biological, contextual, and lifestyle exposures. Our objective was to analyze the time series of CRC incidence and identify its association with urbanization and quality of life in Córdoba, Argentina (2004-2014). A longitudinal ecological study was conducted. Age-standardized incidence rates (ASIR) (standard national and world population) by sex were calculated for Córdoba and its 26 departments for CRC (ICD-10: C18-20), using the provincial tumor registry database. The departments were grouped into three categories, according to the urban scale: High (n=2, cities >400,000 inhabitants); Intermediate (n=13, between 400,000-20,000); and Low (n=11, <20,000). The Quality of Life Index proposed by Velázquez (2010) was employed. Departmental ASIRs were mapped into quintiles. Multilevel modeling was used to estimate the effects (IRR) of sex, time (calendar year), urbanization, and quality of life on ASIRs. Software used: QGis and Stata 17. At the provincial level, CRC ASIRs were 30.9 (95% CI: 29.9-32.0) and 24.3 (95% CI: 23.3-25.3) cases/100,000 for males and females, respectively, and did not decrease over the past decade. Maps reflected differential geospatial patterns by sex. Spatial variability (at the departmental level) indicated high heterogeneity (Var=0.29; 95% CI: 0.16-0.51). The risk of occurrence was significantly higher in males (IRR: 1.63, 95% CI: 1.53-1.76). Lower incidences of this cancer were significantly associated with better quality of life (IRR: 0.28, 95% CI: 0.16-0.47) and inversely with Intermediate urbanization (IRR: 3.65, 95% CI: 1.59-8.41) and Low urbanization (IRR: 7.4, 95% CI: 2.85-19.51). Therefore, despite not decreasing over the past decade, the incidence of CRC, associated with urbanization and poor quality of life, remains more pronounced in the male population. Argentina y, particularmente, Córdoba tienen altas tasas de cáncer colorrectal (CCR), ocupando el segundo lugar tanto en incidencia y mortalidad. Su ocurrencia se correlaciona con exposiciones ambientales, biológicas, de contextos y de estilos de vida. Nuestro objetivo fue analizar la serie temporal de la incidencia del CCR e identificar su asociación con urbanización y calidad de vida, Córdoba, Argentina (2004-2014). Se condujo un estudio ecológico longitudinal. Se calcularon las tasas de incidencia CCR (CIE-10:C18-20) estandarizadas por edad (TIE) (población estándar nacional y mundial) por sexo, para Córdoba y sus 26 departamentos, utilizando la casuística del Registro Provincial de Tumores. Los departamentos se agruparon en tres categorías, según escala urbana (EU): Alta (n=2, ciudades >400.000 habitantes); Intermedia (n=13, entre 400.000-20.000); y Baja (n=11, <20.000). Se utilizó el Índice de Calidad de Vida (ICV) propuesto por Velázquez (2010). Las TIEs departamentales se mapearon en quintiles. Mediante la estrategia de modelado multinivel se estimó del efecto (IRR) del sexo, tiempo (año calendario), urbanización y calidad de vida sobre las TIEs. Softwares: QGis y Stata 17. A nivel provincial, las TIEs de CCR fueron 30,9 (IC 95% 29,9-32,0) y 24,3 (IC 95% 23,3-25,3) casos/100.000 hombres y mujeres, respectivamente, y no disminuyeron en la última década. Los mapas reflejaron patrones geoespaciales diferenciales por sexo. La variabilidad espacial (a nivel departamental) indicó heterogeneidad alta (Var=0,29; IC 95% 0,16-0,51). El riesgo de ocurrencia fue significativamente mayor en hombres (IRR: 1,63, IC 95% 1,53-1,76). Menores incidencias de este cáncer se asociaron significativamente con mejor calidad de vida (IRR: 0,28, IC95% 0,16-0,47) e inversamente con escala urbana Intermedia (IRR: 3,65, IC 95% 1,59-8,41) y Baja (IRR: 7,4, IC 95% 2,85-19,51) . Por lo tanto, sin disminuir en la última década, asociado a la urbanización y baja calidad de vida, la incidencia de CCR continúa siendo más notable en la población masculina. . Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-10-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/42811 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 (2023): Suplemento JIC XXIV Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 (2023): Suplemento JIC XXIV Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 (2023): Suplemento JIC XXIV 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/42811/42832 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |