Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes

Older adults were the segment of the population most affected by the COVID-19 pandemic. Type 2 diabetes (DBT2) also has a high prevalence in this age group, and its preexistence increases susceptibility, severity, and mortality from COVID-19. The objectives of this work were to calculate and compare...

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Autores principales: Ferreyra Pisani, V, Díaz-Gerevini, GT, Priotto, S, López, CB, Pigino, G, Quiroga, P, Repossi, G
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023
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Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/42712
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic Covid-19
Diabetes Mellitus Type 2
older adults
Epidemiology
Covid-19
Diabetes Mellitus Tipo 2
Adultos Mayores
epidemiologia
spellingShingle Covid-19
Diabetes Mellitus Type 2
older adults
Epidemiology
Covid-19
Diabetes Mellitus Tipo 2
Adultos Mayores
epidemiologia
Ferreyra Pisani, V
Díaz-Gerevini, GT
Priotto, S
López, CB
Pigino, G
Quiroga, P
Repossi, G
Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
topic_facet Covid-19
Diabetes Mellitus Type 2
older adults
Epidemiology
Covid-19
Diabetes Mellitus Tipo 2
Adultos Mayores
epidemiologia
author Ferreyra Pisani, V
Díaz-Gerevini, GT
Priotto, S
López, CB
Pigino, G
Quiroga, P
Repossi, G
author_facet Ferreyra Pisani, V
Díaz-Gerevini, GT
Priotto, S
López, CB
Pigino, G
Quiroga, P
Repossi, G
author_sort Ferreyra Pisani, V
title Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
title_short Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
title_full Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
title_fullStr Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
title_full_unstemmed Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes
title_sort epidemiology in older adults of the comorbidity of covid-19 and type 2 diabetes
description Older adults were the segment of the population most affected by the COVID-19 pandemic. Type 2 diabetes (DBT2) also has a high prevalence in this age group, and its preexistence increases susceptibility, severity, and mortality from COVID-19. The objectives of this work were to calculate and compare the main epidemiological variables, between groups with DBT2 and without DBT2 in the study population, before and during the COVID-19 pandemic. To determine if there is an association of higher mortality from COVID-19 with the presence of DBT2 in this population of older adults. Retrospective observational study (2018-2022) of medical records (n=1020) of older adults (≥65 years) treated at the "San Ricardo Pampuri" Center in Villa Carlos Paz. They were statistically analyzed by ANOVA test for quantitative data and Chi-square for categorical data using Infostat (α=0.05). The ethical norms of confidentiality and anonymity were respected. Population data: Gender distribution=62% male/38% female. 47% of the population suffered from DBT2. Total COVID-19 prevalence: 46% of the population (469 cases) during the study period. COVID-19 incidences (%, DBT2 and non-DBT2 patients respectively): 2020: 25.15 vs 15.78; 2021: 22.95 vs. 14.73; 2022: 11.26 vs. 5.38. COVID-19 mortality (%): Total Average=0.63; in DBT2= 1.00 vs. No DBT2=0.32. 72% of the deceased had DBT2. Annual mortality and fatalities from COVID-19 were higher for those with DBT2. In 2020 and 2021 COVID-19 was the leading cause of death in the population studied. Excess Mortality: Average General Mortality (%) pre-pandemic (2018-2019)=1.86 vs pandemic (2020-2022)=2.72 (46% increase). Average age of death from COVID-19: DBT2=76.4; Not DBT2=84.1. 83% of deceased diabetic patients (2020-2022) were not vaccinated against SARS-COV-2. The COVID-19 pandemic had a negative impact on the population parameters studied, with these increases being greater in the group with DBT2. An increased mortality risk for COVID-19 was observed in patients with T2DM. In 2022, there was a large decrease in incidence, mortality, and lethality (general and specific for COVID-19) compared to 2021. The improvement of the variables in 2022 coincides with more than 80% of the population covered with vaccines (≥ 2 doses) against SARS-COV-2
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2023
url https://revistas.unc.edu.ar/index.php/med/article/view/42712
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spelling I10-R327-article-427122023-10-19T21:19:44Z Epidemiology in older adults of the comorbidity of COVID-19 and type 2 diabetes Epidemiología en adultos mayores de la comorbilidad de COVID-19 y diabetes tipo 2 Ferreyra Pisani, V Díaz-Gerevini, GT Priotto, S López, CB Pigino, G Quiroga, P Repossi, G Covid-19 Diabetes Mellitus Type 2 older adults Epidemiology Covid-19 Diabetes Mellitus Tipo 2 Adultos Mayores epidemiologia Older adults were the segment of the population most affected by the COVID-19 pandemic. Type 2 diabetes (DBT2) also has a high prevalence in this age group, and its preexistence increases susceptibility, severity, and mortality from COVID-19. The objectives of this work were to calculate and compare the main epidemiological variables, between groups with DBT2 and without DBT2 in the study population, before and during the COVID-19 pandemic. To determine if there is an association of higher mortality from COVID-19 with the presence of DBT2 in this population of older adults. Retrospective observational study (2018-2022) of medical records (n=1020) of older adults (≥65 years) treated at the "San Ricardo Pampuri" Center in Villa Carlos Paz. They were statistically analyzed by ANOVA test for quantitative data and Chi-square for categorical data using Infostat (α=0.05). The ethical norms of confidentiality and anonymity were respected. Population data: Gender distribution=62% male/38% female. 47% of the population suffered from DBT2. Total COVID-19 prevalence: 46% of the population (469 cases) during the study period. COVID-19 incidences (%, DBT2 and non-DBT2 patients respectively): 2020: 25.15 vs 15.78; 2021: 22.95 vs. 14.73; 2022: 11.26 vs. 5.38. COVID-19 mortality (%): Total Average=0.63; in DBT2= 1.00 vs. No DBT2=0.32. 72% of the deceased had DBT2. Annual mortality and fatalities from COVID-19 were higher for those with DBT2. In 2020 and 2021 COVID-19 was the leading cause of death in the population studied. Excess Mortality: Average General Mortality (%) pre-pandemic (2018-2019)=1.86 vs pandemic (2020-2022)=2.72 (46% increase). Average age of death from COVID-19: DBT2=76.4; Not DBT2=84.1. 83% of deceased diabetic patients (2020-2022) were not vaccinated against SARS-COV-2. The COVID-19 pandemic had a negative impact on the population parameters studied, with these increases being greater in the group with DBT2. An increased mortality risk for COVID-19 was observed in patients with T2DM. In 2022, there was a large decrease in incidence, mortality, and lethality (general and specific for COVID-19) compared to 2021. The improvement of the variables in 2022 coincides with more than 80% of the population covered with vaccines (≥ 2 doses) against SARS-COV-2 Los adultos mayores fueron el segmento de población más afectado por la pandemia de COVID-19. La diabetes tipo 2 (DBT2) también tiene una alta prevalencia en este grupo etario y su preexistencia aumenta la susceptibilidad, gravedad y mortalidad por COVID-19. Los objetivos de este trabajo fueron calcular y comparar las principales variables epidemiológicas, entre grupos con DBT2 y sin DBT2 en la población estudiada, antes y durante la pandemia de COVID-19. Determinar si existe asociación de mayor mortalidad por COVID-19 con la presencia de DBT2 en esta población de adultos mayores. Estudio observacional retrospectivo (2018-2022) de historias clínicas (n=1020) de adultos mayores (≥65 años) atendidos en el Centro “San Ricardo Pampuri” de Villa Carlos Paz. Se analizaron estadísticamente mediante test ANOVA para los datos cuantitativos y Chi cuadrado para los categóricos usando Infostat (α=0.05). Se respetaron las normas éticas de confidencialidad y anonimato. Datos poblacionales: Distribución de sexos=62%masculino/38%femenino. 47% de la población padecía DBT2. Prevalencia total COVID-19: 46% de la población (469 casos) durante el período estudiado. Incidencias COVID-19 (%, pacientes DBT2 y no DBT2 respectivamente):  2020: 25,15 vs 15,78; 2021:  22,95 vs 14,73; 2022: 11,26 vs 5,38. Mortalidad COVID-19 (%): Total Promedio=0,63; en DBT2= 1,00 vs No DBT2=0,32. El 72% de los fallecidos tenían DBT2. Mortalidades y letalidades anuales por COVID-19, fueron mayores para aquellos con DBT2. En 2020 y 2021 COVID-19 fue la principal causa de muerte en la población estudiada. Exceso de Mortalidad: Mortalidad General promedio (%) pre-pandemia (2018-2019)=1,86 vs pandemia (2020-2022)=2,72 (incremento del 46%). Edad promedio fallecimiento por COVID-19: DBT2=76,4; No DBT2=84,1.  El 83% de los pacientes diabéticos fallecidos (2020-2022) no estaban vacunados contra SARS-COV-2. La pandemia de COVID-19 tuvo un impacto negativo sobre los parámetros poblacionales estudiados, siendo estos incrementos mayores en el grupo con DBT2. Se observó un riesgo de mortalidad aumentado para COVID-19 en pacientes con DBT2. En el 2022 se registró una gran disminución de la incidencia, mortalidad y letalidad (gral y específica por COVID-19) respecto al año 2021. El mejoramiento de las variables en 2022 coincide con más del 80% de la población cubierta con vacunas (≥2 dosis) contra SARS-COV-2. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-10-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/42712 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 (2023): Suplemento JIC XXIV Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 (2023): Suplemento JIC XXIV Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 (2023): Suplemento JIC XXIV 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/42712/42882 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0